rhEPO inhibited cell apoptosis to alleviate acute kidney injury in sepsis by AMPK/SIRT1 activated autophagy

Kan Li, Tianxi Liu, Junfeng Li, +7

Biochemical and Biophysical Research Communications

InflammationCell AutophagyCell ApoptosisApoptosisAutophagy +7

Simultaneous Determination of Metformin, Metoprolol and its Metabolites in Rat Plasma by LC–MS-MS: Application to Pharmacokinetic Interaction Study

Yanrong Ma, Zhi Rao, Axi Shi, +10

Journal of Chromatographic Science

EngineeringMs-ms DetectionPharmacokinetic Interaction StudyBiological Mass SpectrometryPharmacotherapy +23

Hesperidin Alleviates Oxidative Stress and Upregulates the Multidrug Resistance Protein 2 in Isoniazid and Rifampicin‐Induced Liver Injury in Rats

Guoqiang Zhang, Jun-Fang Zhu, Yan Zhou, +7

Journal of Biochemical and Molecular Toxicology

PharmacotherapyToxicological MechanismOxidative StressInflammationMolecular Pharmacology +16

Uric acid accumulation in the kidney triggers mast cell degranulation and aggravates renal oxidative stress

Mingkang Zhang, Ruirui Cui, Yan Zhou, +5

Toxicology

InflammationKidney TriggersUrologyRenal FunctionRenal Oxidative Stress +13

An LC-MS/MS analytical method for the determination of uremic toxins in patients with end-stage renal disease

Yanrong Ma, Mingyan Xin, Kan Li, +4

Journal of Pharmaceutical and Biomedical Analysis

HemodialysisUrologyLc-ms/ms Analytical MethodRenal FunctionMedicine +13

Erythropoietin promotes energy metabolism to improve LPS-induced injury in HK-2 cells via SIRT1/PGC1-α pathway

Kan Li, Li Gao, Sen Zhou, +6

Molecular and Cellular Biochemistry

InflammationEnergy MetabolismCell SignalingHk-2 CellsApoptosis +8

Albumin-bound kynurenic acid is an appropriate endogenous biomarker for assessment of the renal tubular OATs-MRP4 channel

Yanrong Ma, Fenglin Ran, Mingyan Xin, +3

Journal of Pharmaceutical Analysis

Effect of cholecystectomy on bile acids as well as relevant enzymes and transporters in mice: Implication for pharmacokinetic changes of rifampicin

Fan Zhang, Hongyan Qin, Yanshu Zhao, +7

European Journal of Pharmaceutical Sciences

Biliary TractMedicineLiver PhysiologyPathologyBiliary Disorder +7

Inhibitory effect of atenolol on urinary excretion of metformin via down-regulating multidrug and toxin extrusion protein 1 (rMate1) expression in the kidney of rats

Yanrong Ma, Huang Jing, Yun‐yun Shao, +6

European Journal of Pharmaceutical Sciences

UrologyRenal FunctionUrinary ExcretionMedicinePhysiology +8

Development of a LC‐MS/MS method for simultaneous determination of metoprolol and its metabolites, <i>α</i>‐hydroxymetoprolol and <i>O</i>‐desmethylmetoprolol, in rat plasma: application to the herb–drug interaction study of metoprolol and breviscapine

Zhi Rao, Yanrong Ma, Hongyan Qin, +6

Biomedical Chromatography