Joshua G. Pierce

A Redesigned Vancomycin Engineered for Dual <scp>d</scp> -Ala- <scp>d</scp> -Ala and <scp>d</scp> -Ala- <scp>d</scp> -Lac Binding Exhibits Potent Antimicrobial Activity Against Vancomycin-Resistant Bacteria

Jian Xie, Joshua G. Pierce, Robert C. James et al. · Journal of the American Chemical Society · 2011 · 134 citations

Total Synthesis of [Ψ[C(═S)NH]Tpg⁴]Vancomycin Aglycon, [Ψ[C(═NH)NH]Tpg⁴]Vancomycin Aglycon, and Related Key Compounds: Reengineering Vancomycin for Dual <scp>d</scp>-Ala-<scp>d</scp>-Ala and <scp>d</scp>-Ala-<scp>d</scp>-Lac Binding

Jian Xie, Akinori Okano, Joshua G. Pierce et al. · Journal of the American Chemical Society · 2011 · 129 citations

Medicinal Chemistry, Diversity Oriented Synthesis, Derivatives +12

Redesign of Glycopeptide Antibiotics: Back to the Future

Robert C. James, Joshua G. Pierce, Akinori Okano et al. · ACS Chemical Biology · 2012 · 115 citations · Full text

Bioorganic Chemistry, Glycobiology, Antimicrobial Chemotherapy +18

Silver(I)-Promoted Conversion of Thioamides to Amidines: Divergent Synthesis of a Key Series of Vancomycin Aglycon Residue 4 Amidines That Clarify Binding Behavior to Model Ligands

Akinori Okano, Robert C. James, Joshua G. Pierce et al. · Journal of the American Chemical Society · 2012 · 73 citations · Full text

Medicinal Chemistry, Key Series, Bioorganic Chemistry +14

The mitochondria-targeted nitroxide JP4-039 augments potentially lethal irradiation damage repair.

Malolan S. Rajagopalan, Kanika Gupta, Michael W. Epperly et al. · PubMed · 2009 · 55 citations · Full text

Engineering, Radiation Effect, Radiation Exposure +19