Mairi Challinor

Dynamic Gene Regulatory Networks Drive Hematopoietic Specification and Differentiation

Debbie K. Goode, Nadine Obier, M. S. Vijayabaskar et al. · Developmental Cell · 2016 · 256 citations · Full text

Structure-Guided Design of Highly Selective and Potent Covalent Inhibitors of ERK1/2

Richard A. Ward, Nicola Colclough, Mairi Challinor et al. · Journal of Medicinal Chemistry · 2015 · 102 citations · Full text

Small Molecule Inhibitors, Covalent Inhibitors, Drug Target +17

Anti-metastatic Inhibitors of Lysyl Oxidase (LOX): Design and Structure–Activity Relationships

Leo Leung, Dan Niculescu‐Duvaz, Deborah A. Smithen et al. · Journal of Medicinal Chemistry · 2019 · 64 citations · Full text

Regulation of RUNX1 dosage is crucial for efficient blood formation from hemogenic endothelium

Michael Lie‐A‐Ling, Elli Marinopoulou, Andrew J. Lilly et al. · Development · 2018 · 51 citations · Full text

2-Aminomethylene-5-sulfonylthiazole Inhibitors of Lysyl Oxidase (LOX) and LOXL2 Show Significant Efficacy in Delaying Tumor Growth

Deborah A. Smithen, Leo Leung, Mairi Challinor et al. · Journal of Medicinal Chemistry · 2019 · 40 citations · Full text

Dual Lox/loxl2 Inhibitors, Drug Target, Loxl2 Inhibition +19