Tumor αvβ3 Integrin Is a Therapeutic Target for Breast Cancer Bone Metastases

Yingshe Zhao, Richard Bachelier, Isabelle Treilleux, +5

Cancer Research

Ezrin Regulates E-Cadherin-dependent Adherens Junction Assembly through Rac1 Activation

Philippe Pujuguet, Laurence Del Maestro, Alexis Gautreau, +2

Molecular Biology of the Cell

Rac1 ActivationCell AdhesionEzrin T567dMolecular BiologyCytoskeleton +14

<i>In vivo</i> and <i>in vitro</i> invasiveness of a rat colon‐cancer cell line maintaining E‐cadherin expression: An enhancing role of tumor‐associated myofibroblasts

Marie Thearèse Dimanche‐Boitrel, L. Vakaet, Philippe Pujuguet, +6

International Journal of Cancer

Targeting of αv-Integrins in Stem/Progenitor Cells and Supportive Microenvironment Impairs Bone Metastasis in Human Prostate Cancer

Geertje van der Horst, Christel van den Hoogen, Jeroen T. Buijs, +10

Neoplasia

Characterization of BCE-1, a Transcriptional Enhancer Regulated by Prolactin and Extracellular Matrix and Modulated by the State of Histone Acetylation

Connie A. Myers, Christian Schmidhauser, Julia Mellentin-Michelotti, +7

Molecular and Cellular Biology

A multiparameter approach to monitor disease activity in collagen-induced arthritis

Sylvie Seeuws, Peggy Jacques, Jens Van Praet, +11

Arthritis Research & Therapy

The Medium-Chain Fatty Acid Receptor GPR84 Mediates Myeloid Cell Infiltration Promoting Steatohepatitis and Fibrosis

Tobias Puengel, Steve De Vos, Jana Hundertmark, +13

Journal of Clinical Medicine

Liver FibrosisImmunologyPathologyFatty Liver DiseaseMcfa Receptor Gpr84 +18

Expression of fibronectin ED-A+ and ED-B+ isoforms by human and experimental colorectal cancer. Contribution of cancer cells and tumor-associated myofibroblasts.

Philippe Pujuguet, Arlette Hammann, Monique Moutet, +3

PubMed

A dose escalating phase I study of GLPG0187, a broad spectrum integrin receptor antagonist, in adult patients with progressive high-grade glioma and other advanced solid malignancies

Geert A. Cirkel, Bojana Milojkovic Kerklaan, Frédéric Vanhoutte, +10

Investigational New Drugs

Genetic depletion and pharmacological targeting of αv integrin in breast cancer cells impairs metastasis in zebrafish and mouse xenograft models

Yihao Li, Yvette Drabsch, Philippe Pujuguet, +6

Breast Cancer Research