Joshua Straka

Genomic Analysis of Dysembryoplastic Neuroepithelial Tumor Spectrum Reveals a Diversity of Molecular Alterations Dysregulating the MAPK and PI3K/mTOR Pathways

Lea F. Surrey, Payal Jain, Bo Zhang et al. · Journal of Neuropathology & Experimental Neurology · 2019 · 62 citations · Full text

Medicine, Genetics, Oncology +17

Multi-step processing of replication stress-derived nascent strand DNA gaps by MRE11 and EXO1 nucleases

Anastasia Hale, Ashna Dhoonmoon, Joshua Straka et al. · Nature Communications · 2023 · 49 citations · Full text

Life Sciences, Molecular Biology, Toxicology +17

Lagging strand gap suppression connects BRCA-mediated fork protection to nucleosome assembly through PCNA-dependent CAF-1 recycling

Tanay Thakar, Ashna Dhoonmoon, Joshua Straka et al. · Nature Communications · 2022 · 34 citations · Full text

Life Sciences, Cancer Biology, Molecular Biology +17

BRAF fusions in pediatric histiocytic neoplasms define distinct therapeutic responsiveness to RAF paradox breakers

Payal Jain, Lea F. Surrey, Joshua Straka et al. · Pediatric Blood & Cancer · 2021 · 18 citations

Medicine, Molecular Genetics, Oncology +17

Sclerosing Epithelioid Fibrosarcoma of the Bone With Rare EWSR1-CREB3L3 Translocation Driving Upregulation of the PI3K/mTOR Signaling Pathway

Archana Shenoy, Lea F. Surrey, Payal Jain et al. · Pediatric and Developmental Pathology · 2019 · 13 citations

Medicine, Oncology, Pathology +17