Tanay Thakar

Ubiquitinated-PCNA protects replication forks from DNA2-mediated degradation by regulating Okazaki fragment maturation and chromatin assembly

Tanay Thakar, Wendy Leung, Claudia M. Nicolae et al. · Nature Communications · 2020 · 138 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Activation of Wnt signaling promotes olaparib resistant ovarian cancer

Tomomi M. Yamamoto, Alexandra McMellen, Zachary L. Watson et al. · Molecular Carcinogenesis · 2019 · 101 citations · Full text

Medicine, Oncology, Pharmacology +17

SMARCAL1 is a dual regulator of innate immune signaling and PD-L1 expression that promotes tumor immune evasion

Giuseppe Leuzzi, Alessandro Vasciaveo, Angelo Taglialatela et al. · Cell · 2024 · 93 citations · Full text

Medicine, Immunology, Oncology +16

Loss of E2F7 confers resistance to poly-ADP-ribose polymerase (PARP) inhibitors in BRCA2-deficient cells

Kristen E. Clements, Tanay Thakar, Claudia M. Nicolae et al. · Nucleic Acids Research · 2018 · 73 citations · Full text

Medicine, Molecular Biology, Oncology +13

Identification of regulators of poly-ADP-ribose polymerase inhibitor response through complementary CRISPR knockout and activation screens

Kristen E. Clements, Emily M. Schleicher, Tanay Thakar et al. · Nature Communications · 2020 · 53 citations · Full text

Life Sciences, Genetics, Molecular Biology +17