Kristen E. Clements

Ubiquitinated-PCNA protects replication forks from DNA2-mediated degradation by regulating Okazaki fragment maturation and chromatin assembly

Tanay Thakar, Wendy Leung, Claudia M. Nicolae et al. · Nature Communications · 2020 · 138 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Loss of E2F7 confers resistance to poly-ADP-ribose polymerase (PARP) inhibitors in BRCA2-deficient cells

Kristen E. Clements, Tanay Thakar, Claudia M. Nicolae et al. · Nucleic Acids Research · 2018 · 73 citations · Full text

Medicine, Molecular Biology, Oncology +13

Identification of regulators of poly-ADP-ribose polymerase inhibitor response through complementary CRISPR knockout and activation screens

Kristen E. Clements, Emily M. Schleicher, Tanay Thakar et al. · Nature Communications · 2020 · 53 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Genome-wide CRISPR synthetic lethality screen identifies a role for the ADP-ribosyltransferase PARP14 in DNA replication dynamics controlled by ATR

Ashna Dhoonmoon, Emily M. Schleicher, Kristen E. Clements et al. · Nucleic Acids Research · 2020 · 30 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Dual genome-wide CRISPR knockout and CRISPR activation screens identify mechanisms that regulate the resistance to multiple ATR inhibitors

Emily M. Schleicher, Ashna Dhoonmoon, Lindsey M. Jackson et al. · PLoS Genetics · 2020 · 28 citations · Full text

Life Sciences, Molecular Biology, Oncology +17