Concepedia

Nicholas Smithers

NS

Statistics

Publications

24

Citations

2K

H-Index

20

Active since

1997

Affiliations

GlaxoSmithKline (United Kingdom)(Current)

Age UK

Imperial College London

The University of Sydney

University of Strathclyde

Nicholas Smithers is an author at GlaxoSmithKline (United Kingdom) specializing in life sciences, molecular biology, and epigenetics.

ORCID

Publications per year

1997–2022

24

Publications

24

Discovery of Epigenetic Regulator I-BET762: Lead Optimization to Afford a Clinical Candidate Inhibitor of the BET Bromodomains

Olivier Mirguet, Romain Gosmini, Jérôme Toum et al. · Journal of Medicinal Chemistry · 2013 · 304 citations · Full text

, , +17

The BAFF Receptor Transduces Survival Signals by Co-opting the B Cell Receptor Signaling Pathway

Edina Schweighoffer, Lesley Vanes, Josquin Nys et al. · Immunity · 2013 · 210 citations · Full text

, , +17

Potent antimyeloma activity of the novel bromodomain inhibitors I-BET151 and I-BET762

Aristeidis Chaidos, Valentina S. Caputo, Katerina Gouvedenou et al. · Blood · 2013 · 202 citations

, , +6

Selective inhibition of CD4 <sup>+</sup> T-cell cytokine production and autoimmunity by BET protein and c-Myc inhibitors

Hozefa S. Bandukwala, John D Gagnon, Susan Togher et al. · Proceedings of the National Academy of Sciences · 2012 · 185 citations · Full text

, , +17

CLEC-2 and Syk in the megakaryocytic/platelet lineage are essential for development

Brenda Finney, Edina Schweighoffer, Leyre Navarro‐Núñez et al. · Blood · 2011 · 154 citations · Full text

, , +5

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