An Aneuploid Mouse Strain Carrying Human Chromosome 21 with Down Syndrome Phenotypes

Aideen O’Doherty, Sandra Ruf, Claire Mulligan, +15

Science

Down SyndromeChromatinKnockout MouseDevelopmental BiologyCytogenetics +13

Species-Specific Transcription in Mice Carrying Human Chromosome 21

Michael D. Wilson, Nuno L. Barbosa‐Morais, Dominic Schmidt, +6

Science

CytogeneticsGeneticsMolecular GeneticsEpigeneticsTranscriptional Regulation +16

Critical Roles for Rac1 and Rac2 GTPases in B Cell Development and Signaling

Marita J. Walmsley, Steen K.T. Ooi, Lucinda F. Reynolds, +7

Science

Signal TransductionDevelopmental BiologyRac2 GtpasesSignaling PathwayImmune Cell Development +13

The BAFF Receptor Transduces Survival Signals by Co-opting the B Cell Receptor Signaling Pathway

Edina Schweighoffer, Lesley Vanes, Josquin Nys, +4

Immunity

Dissecting NK cell development using a novel alymphoid mouse model: investigating the role of the c-abl proto-oncogene in murine NK cell differentiation.

Francesco Colucci, Claire Soudais, Eleftheria Rosmaraki, +3

PubMed

Lymphocyte DevelopmentAdaptive Immune SystemImmunologyNk CellsImmunologic Mechanism +17

Dissecting NK Cell Development Using a Novel Alymphoid Mouse Model: Investigating the Role of the c-<i>abl</i> Proto-Oncogene in Murine NK Cell Differentiation

Francesco Colucci, Claire Soudais, Eleftheria Rosmaraki, +3

The Journal of Immunology

An Unexpected Role for IL-3 in the Embryonic Development of Hematopoietic Stem Cells

Catherine Robin, Katrin Ottersbach, Charles Durand, +4

Developmental Cell

Developmental BiologyLymphocyte DevelopmentMedicineStem Cell MobilizationHematology +11

Unexpected Requirement for ZAP-70 in Pre-B Cell Development and Allelic Exclusion

Edina Schweighoffer, Lesley Vanes, Anne Mathiot, +2

Immunity

Cell LineageDevelopmental BiologyAllelic ExclusionUnexpected RequirementImmune Cell Development +7

Preservation of long-term memory and synaptic plasticity despite short-term impairments in the Tc1 mouse model of Down syndrome

Élise Morice, Laura C. Andreae, Samuel F. Cooke, +4

Learning & Memory

TLR4 signals in B lymphocytes are transduced via the B cell antigen receptor and SYK

Edina Schweighoffer, Josquin Nys, Lesley Vanes, +2

The Journal of Experimental Medicine

Microbial PathogensAdaptive Immune SystemT-regulatory CellInnate Immune SystemImmunology +25