Frank H. Ebetino

Structure-Activity Relationships for Inhibition of Farnesyl Diphosphate Synthase in Vitro and Inhibition of Bone Resorption in Vivo by Nitrogen-Containing Bisphosphonates

James E. Dunford, Keith Thompson, Fraser P. Coxon et al. · Journal of Pharmacology and Experimental Therapeutics · 2001 · 896 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Novel insights into actions of bisphosphonates on bone: Differences in interactions with hydroxyapatite

George H. Nancollas, Ruikang Tang, Roger Phipps et al. · Bone · 2005 · 859 citations

Medicine, Orthopaedic Surgery, Orthopedic Surgery +12

Bisphosphonates inhibit breast and prostate carcinoma cell invasion, an early event in the formation of bone metastases.

S. Boissier, Mercedes Ferreras, Olivier Peyruchaud et al. · PubMed · 2000 · 573 citations

Medicine, Oncology, Pharmacology +17

The molecular mechanism of nitrogen-containing bisphosphonates as antiosteoporosis drugs

K.L. Kavanagh, Kunde Guo, James E. Dunford et al. · Proceedings of the National Academy of Sciences · 2006 · 532 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Osteoclasts recycle via osteomorphs during RANKL-stimulated bone resorption

Michelle M. McDonald, Weng Hua Khoo, Pei Ying Ng et al. · Cell · 2021 · 413 citations · Full text

Medicine, Cell Biology, Molecular Biology +17