Sérgio T. Ferreira

Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer’s models

Mychael V. Lourenco, Rudimar Luiz Frozza, Guilherme B. de Freitas et al. · Nature Medicine · 2018 · 882 citations · Full text

Synaptic Plasticity, Neurodegenerative Diseases, Alzheimer's Disease +11

Aβ Oligomers Induce Neuronal Oxidative Stress through an N-Methyl-D-aspartate Receptor-dependent Mechanism That Is Blocked by the Alzheimer Drug Memantine

Fernanda G. De Felice, Pauline T. Velasco, Mary P. Lambert et al. · Journal of Biological Chemistry · 2007 · 867 citations · Full text

An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer’s disease–associated Aβ oligomers

Theresa R. Bomfim, Letícia Forny‐Germano, Luciana B. Sathler et al. · Journal of Clinical Investigation · 2012 · 812 citations · Full text

Synaptic Transmission, Synaptic Signaling, Insulin Signaling +28

Protection of synapses against Alzheimer's-linked toxins: Insulin signaling prevents the pathogenic binding of Aβ oligomers

Fernanda G. De Felice, Marcelo N. N. Vieira, Theresa R. Bomfim et al. · Proceedings of the National Academy of Sciences · 2009 · 657 citations · Full text

TNF-α Mediates PKR-Dependent Memory Impairment and Brain IRS-1 Inhibition Induced by Alzheimer’s β-Amyloid Oligomers in Mice and Monkeys

Mychael V. Lourenco, Julia R. Clarke, Rudimar Luiz Frozza et al. · Cell Metabolism · 2013 · 407 citations · Full text

Neurodegenerative Diseases, β-Amyloid Oligomers, Alzheimer's Disease +13