Concepedia
5
Publications
244
Citations
H-Index
2020
Active since
Affiliations
University of Leicester(Current)
Joshua P. Smalley is an author at University of Leicester.
Publications per year
2020–2023
PROTAC-mediated degradation of class I histone deacetylase enzymes in corepressor complexes
Joshua P. Smalley, Grace E. Adams, Christopher J. Millard et al. · Chemical Communications · 2020 · 108 citations · Full text
Optimization of Class I Histone Deacetylase PROTACs Reveals that HDAC1/2 Degradation is Critical to Induce Apoptosis and Cell Arrest in Cancer Cells
Joshua P. Smalley, India M Baker, Wiktoria A. Pytel et al. · Journal of Medicinal Chemistry · 2022 · 74 citations · Full text
Comprehensive Transcriptomic Analysis of Novel Class I HDAC Proteolysis Targeting Chimeras (PROTACs)
India M Baker, Joshua P. Smalley, Khadija A Sabat et al. · Biochemistry · 2022 · 28 citations · Full text
A ‘click’ chemistry approach to novel entinostat (MS-275) based class I histone deacetylase proteolysis targeting chimeras
Jasmine M. Cross, Megan E. Coulson, Joshua P. Smalley et al. · RSC Medicinal Chemistry · 2022 · 23 citations · Full text
MDM2 Antagonist Idasanutlin Reduces HDAC1/2 Abundance and Corepressor Partners but Not HDAC3
Joshua P. Smalley, Shaun M. Cowley, James T. Hodgkinson · ACS Medicinal Chemistry Letters · 2023 · 11 citations · Full text
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