James T. Hodgkinson

Diversity-oriented synthesis of macrocyclic peptidomimetics

Albert Isidro‐Llobet, Tiffanie Murillo, Paula Bello et al. · Proceedings of the National Academy of Sciences · 2011 · 115 citations · Full text

Combinatorial Chemistry, Diverse Libraries, Engineering +17

PROTAC-mediated degradation of class I histone deacetylase enzymes in corepressor complexes

Joshua P. Smalley, Grace E. Adams, Christopher J. Millard et al. · Chemical Communications · 2020 · 108 citations · Full text

Inhibition of the production of the Pseudomonas aeruginosa virulence factor pyocyanin in wild-type cells by quorum sensing autoinducer-mimics

Bernardas Morkunas, Warren R. J. D. Galloway, Megan H. Wright et al. · Organic & Biomolecular Chemistry · 2012 · 77 citations

Antimicrobial Resistance Gene, Quorum Sensing, Antibiotics +15

Design, synthesis and biological evaluation of non-natural modulators of quorum sensing in Pseudomonas aeruginosa

James T. Hodgkinson, Warren R. J. D. Galloway, Megan H. Wright et al. · Organic & Biomolecular Chemistry · 2012 · 74 citations

Bioorganic Chemistry, Quorum Sensing, Natural Sciences +12

Optimization of Class I Histone Deacetylase PROTACs Reveals that HDAC1/2 Degradation is Critical to Induce Apoptosis and Cell Arrest in Cancer Cells

Joshua P. Smalley, India M Baker, Wiktoria A. Pytel et al. · Journal of Medicinal Chemistry · 2022 · 74 citations · Full text