Bjoern Bielec

The thiosemicarbazone Me2NNMe2 induces paraptosis by disrupting the ER thiol redox homeostasis based on protein disulfide isomerase inhibition

Sonja Hager, Katharina Korbula, Bjoern Bielec et al. · Cell Death and Disease · 2018 · 69 citations · Full text

Understanding the metabolism of the anticancer drug Triapine: electrochemical oxidation, microsomal incubation and in vivo analysis using LC-HRMS

Karla Pelivan, Lisa M. Frensemeier, Uwe Kärst et al. · The Analyst · 2017 · 18 citations · Full text

Metabolomic Profiling, Cellular Pharmacology, Pharmaceutical Chemistry +21

Development and biological investigations of hypoxia-sensitive prodrugs of the tyrosine kinase inhibitor crizotinib

Bjoern Bielec, Hemma Schueffl, Alessio Terenzi et al. · Bioorganic Chemistry · 2020 · 18 citations · Full text

Biological Investigations, Biochemistry, Medicine +7

Mechanistic aspects of the direct C-acylation of cyclic 1,3-diones with various unactivated carboxylic acids

Michal Kohout, Bjoern Bielec, Patrick Steindl et al. · Tetrahedron · 2015 · 14 citations

Cross-coupling Reaction, Engineering, Mechanistic Aspects +7

Reactive Oxygen Species (ROS)-Sensitive Prodrugs of the Tyrosine Kinase Inhibitor Crizotinib

Bjoern Bielec, Isabella Poetsch, Esra Ahmed et al. · Molecules · 2020 · 11 citations · Full text