Christian W. Johnson

Tissue-Specific Oncogenic Activity of KRASA146T

Emily J. Poulin, Asim K. Bera, Jia Lu et al. · Cancer Discovery · 2019 · 189 citations · Full text

The small GTPases K-Ras, N-Ras, and H-Ras have distinct biochemical properties determined by allosteric effects

Christian W. Johnson, Derion Reid, Jillian A. Parker et al. · Journal of Biological Chemistry · 2017 · 132 citations · Full text

Distinct Biochemical Properties, Signal Transduction, Biochemistry +12

Classification of <i>KRAS</i> -Activating Mutations and the Implications for Therapeutic Intervention

Christian W. Johnson, Deborah L. Burkhart, Kevin M. Haigis · Cancer Discovery · 2022 · 98 citations · Full text

Isoform-Specific Destabilization of the Active Site Reveals a Molecular Mechanism of Intrinsic Activation of KRas G13D

Christian W. Johnson, Yi-Jang Lin, Derion Reid et al. · Cell Reports · 2019 · 84 citations · Full text

Tyrosine phosphorylation of RAS by ABL allosterically enhances effector binding

Pamela Y. Ting, Christian W. Johnson, Cong Fang et al. · The FASEB Journal · 2015 · 46 citations · Full text

Effector Binding, Ras Effector Ras-, Tyrosine 137 +16