Chemically defined generation of human cardiomyocytes

Paul W. Burridge, Elena Matsa, Praveen Shukla, +12

Nature Methods

Regenerative MedicineCardiac MuscleCardiomyopathyMolecular PhysiologyCardiac Reprogramming +10

The Translational Landscape of the Human Heart

Sebastiaan van Heesch, Franziska Witte, Valentin Schneider-Lunitz, +52

Cell

Heart FailureStructural Heart DiseaseTranslational LandscapeAnthropologyMedicine +3

Drug Screening Using a Library of Human Induced Pluripotent Stem Cell–Derived Cardiomyocytes Reveals Disease-Specific Patterns of Cardiotoxicity

Ping Liang, Feng Lan, Andrew S. Lee, +11

Circulation

E‐cadherin is crucial for embryonic stem cell pluripotency and can replace OCT4 during somatic cell reprogramming

Torben Redmer, Sebastian Diecke, Tamara Grigoryan, +3

EMBO Reports

Embryonic Stem CellInduced Pluripotent Stem CellDevelopmental BiologyMedicineStem Cell Research +5

Activation of PDGF pathway links LMNA mutation to dilated cardiomyopathy

Jaecheol Lee, Vittavat Termglinchan, Sebastian Diecke, +21

Nature

Cardiac MuscleCardiomyopathyHeart FailureSystems BiologyMolecular Physiology +6

Electroconductive Biohybrid Hydrogel for Enhanced Maturation and Beating Properties of Engineered Cardiac Tissues

Kaveh Roshanbinfar, Lena Vogt, Boris Greber, +4

Advanced Functional Materials

Tissue EngineeringHeart FailureEngineeringBiomimetic MaterialsBiomaterials Design +21

Transplanted terminally differentiated induced pluripotent stem cells are accepted by immune mechanisms similar to self-tolerance

Patricia E. de Almeida, Everett Meyer, Nigel G. Kooreman, +13

Nature Communications

Regenerative MedicineCell TherapyInduced Pluripotent Stem CellTransplantationMedicine +11

Autologous iPSC-Based Vaccines Elicit Anti-tumor Responses In Vivo

Nigel G. Kooreman, Youngkyun Kim, Patrícia E. de Almeida, +16

Cell stem cell

VaccinationTumor ImmunologyImmunologyTherapeutic VaccineVaccine Design +2

Human Induced Pluripotent Stem Cell–Derived Cardiomyocytes as an In Vitro Model for Coxsackievirus B3–Induced Myocarditis and Antiviral Drug Screening Platform

Arun Sharma, Caleb Marceau, Ryoko Hamaguchi, +15

Circulation Research

Mutations in Disordered Regions Can Cause Disease by Creating Dileucine Motifs

Katrina Meyer, Marieluise Kirchner, Bora Uyar, +15

Cell

Dileucine MotifsMendelian DisorderGenetic DisorderGeneticsPathogenesis +6