Concepedia

Activation of PDGF pathway links LMNA mutation to dilated cardiomyopathy

Jaecheol Lee, Vittavat Termglinchan, Sebastian Diecke, Ilanit Itzhaki, Chi Keung Lam, Priyanka Garg, Edward Lau, Matthew Greenhaw, Timon Seeger, Haodi Wu,

Nature · 2019 · 219 citations · 30 references

Concepts

MedicineGeneticsMolecular BiologyCardiovascular GeneticsClinical CardiologySignal TransductionCongenital Heart DiseaseCongenital Heart Disease GeneticsDilated Cardiomyopathy GeneticsInherited CardiomyopathiesMendelian Cardiovascular DisordersCardiomyopathy Genotype-phenotype CorrelationCongenital Heart Defect MutationsLmna-associated Cardiomyopathy

References

30

Fast gapped-read alignment with Bowtie 2

Ben Langmead, Steven L. Salzberg · Nature Methods · 2012 · 61.1K citations

Life Sciences, Bioinformatics, Molecular Biology +11

Tissue-based map of the human proteome

Mathias Uhlén, Linn Fagerberg, Björn M. Hallström et al. · Science · 2015 · 15.9K citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +17

Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position

Jason D. Buenrostro, Paul G. Giresi, Lisa C. Zaba et al. · Nature Methods · 2013 · 7K citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Software for Computing and Annotating Genomic Ranges

Michael Lawrence, Wolfgang Huber, Hervé Pagès et al. · PLoS Computational Biology · 2013 · 5K citations · Full text

Life Sciences, Bioinformatics, Genetics +16

deepTools: a flexible platform for exploring deep-sequencing data

Fidel Ramírez, Friederike Dündar, Sarah Diehl et al. · Nucleic Acids Research · 2014 · 4.2K citations · Full text

Life Sciences, Bioinformatics, Visualization +11