Jacob R. Hambrook

Coordination of humoral immune factors dictates compatibility between Schistosoma mansoni and Biomphalaria glabrata

Hongyu Li, Jacob R. Hambrook, Emmanuel A. Pila et al. · eLife · 2020 · 48 citations · Full text

Life Sciences, Immunology, Infectious Diseases +17

Sasanquasaponin ΙΙΙ from Schima crenata Korth induces autophagy through Akt/mTOR/p70S6K pathway and promotes apoptosis in human melanoma A375 cells

Qiu-Ping Liang, Tianqi Xu, Bai-Lian Liu et al. · Phytomedicine · 2018 · 35 citations

Life Sciences, Cell Biology, Oncology +12

A metalloprotease produced by larval Schistosoma mansoni facilitates infection establishment and maintenance in the snail host by interfering with immune cell function

Jacob R. Hambrook, Alèthe L. Kaboré, Emmanuel A. Pila et al. · PLoS Pathogens · 2018 · 32 citations · Full text

Veterinary Medicine, Immunology, Infectious Diseases +17

Single-cell RNA-seq profiling of individual Biomphalaria glabrata immune cells with a focus on immunologically relevant transcripts

Hongyu Li, Abdullah A. Gharamah, Jacob R. Hambrook et al. · Immunogenetics · 2021 · 19 citations

Life Sciences, Immunology, Molecular Biology +15

Biomphalaria glabrata Granulin Increases Resistance to Schistosoma mansoni Infection in Several Biomphalaria Species and Induces the Production of Reactive Oxygen Species by Haemocytes

Jacob R. Hambrook, Abdullah A. Gharamah, Emmanuel A. Pila et al. · Genes · 2019 · 12 citations · Full text

Life Sciences, Biology, Immunology +17