Daniel Mutisya

Amides are excellent mimics of phosphate internucleoside linkages and are well tolerated in short interfering RNAs

Daniel Mutisya, Chelliah Selvam, Benjamin D. Lunstad et al. · Nucleic Acids Research · 2014 · 60 citations · Full text

Amide linkages mimic phosphates in RNA interactions with proteins and are well tolerated in the guide strand of short interfering RNAs

Daniel Mutisya, Travis Hardcastle, Samwel K. Cheruiyot et al. · Nucleic Acids Research · 2017 · 44 citations · Full text

Biochemistry, Mimic Phosphates, Protein Folding +15

Synthesis and properties of triazole-linked RNA

Daniel Mutisya, Chelliah Selvam, Scott D. Kennedy et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 29 citations

Triazole-linked Rna, Rna Structure Prediction, Rna Biology +1

A Single Amide Linkage in the Passenger Strand Suppresses Its Activity and Enhances Guide Strand Targeting of siRNAs

Travis Hardcastle, Irina Novosjolova, Venubabu Kotikam et al. · ACS Chemical Biology · 2018 · 28 citations · Full text

Biochemistry, Rna Interference, Passenger Strand Suppresses +13