Concepedia

K N Fedde

KN

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Publications

16

Citations

1.6K

H-Index

15

Active since

1984

Affiliations

Washington University in St. Louis(Current)

Shriners Hospitals for Children - Erie

University of Pennsylvania

Medical College of Wisconsin

Shriners Hospitals for Children - St. Louis

K N Fedde is an author at Washington University in St. Louis specializing in medicine, pathology, and metabolism.

Top concepts

Publications per year

1984–1999

16

Publications

16

Alkaline Phosphatase Knock-Out Mice Recapitulate the Metabolic and Skeletal Defects of Infantile Hypophosphatasia

K N Fedde, Libby A. Blair, Julie Silverstein et al. · Journal of Bone and Mineral Research · 1999 · 394 citations · Full text

Different missense mutations at the tissue-nonspecific alkaline phosphatase gene locus in autosomal recessively inherited forms of mild and severe hypophosphatasia.

Paula S. Henthorn, M Raducha, K N Fedde et al. · Proceedings of the National Academy of Sciences · 1992 · 258 citations · Full text

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Alkaline phosphatase: placental and tissue-nonspecific isoenzymes hydrolyze phosphoethanolamine, inorganic pyrophosphate, and pyridoxal 5'-phosphate. Substrate accumulation in carriers of hypophosphatasia corrects during pregnancy.

Michael P. Whyte, M Landt, Louise Ryan et al. · Journal of Clinical Investigation · 1995 · 165 citations · Full text

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Matrix vesicles in osteomalacic hypophosphatasia bone contain apatite-like mineral crystals.

H. Clarke Anderson, Howard H.T. Hsu, David C. Morris et al. · PubMed · 1997 · 120 citations

Perinatal hypophosphatasia: tissue levels of vitamin B6 are unremarkable despite markedly increased circulating concentrations of pyridoxal-5'-phosphate. Evidence for an ectoenzyme role for tissue-nonspecific alkaline phosphatase.

Michael P. Whyte, J. Dennis Mahuren, K N Fedde et al. · Journal of Clinical Investigation · 1988 · 109 citations · Full text

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