Mathilde H. Lerche

Increase in signal-to-noise ratio of > 10,000 times in liquid-state NMR

Jan Henrik Ardenkjær‐Larsen, Björn Fridlund, Andreas Gram et al. · Proceedings of the National Academy of Sciences · 2003 · 2.8K citations · Full text

Natural Sciences, Biophysics, Chemistry +17

Detecting tumor response to treatment using hyperpolarized 13C magnetic resonance imaging and spectroscopy

Sam E. Day, Mikko I. Kettunen, Ferdia A. Gallagher et al. · Nature Medicine · 2007 · 884 citations

Medicine, Oncology, Radiology +14

Magnetic resonance imaging of pH in vivo using hyperpolarized 13C-labelled bicarbonate

Ferdia A. Gallagher, Mikko I. Kettunen, Sam E. Day et al. · Nature · 2008 · 846 citations

Natural Sciences, Biophysics, Chemistry +14

Metabolic Imaging by Hyperpolarized 13C Magnetic Resonance Imaging for <i>In vivo</i> Tumor Diagnosis

Klaes Golman, René in ‘t Zandt, Mathilde H. Lerche et al. · Cancer Research · 2006 · 585 citations · Full text

Life Sciences, Biochemistry, Oncology +17

Production of hyperpolarized [1,4- ¹³ C ₂ ]malate from [1,4- ¹³ C ₂ ]fumarate is a marker of cell necrosis and treatment response in tumors

Ferdia A. Gallagher, Mikko I. Kettunen, De‐En Hu et al. · Proceedings of the National Academy of Sciences · 2009 · 304 citations · Full text

Medicine, Biochemistry, Oncology +10