CCR7 Is Critically Important for Migration of Dendritic Cells in Intestinal Lamina Propria to Mesenteric Lymph Nodes

Myoung Ho Jang, Nagako Sougawa, Toshiyuki Tanaka, +11

The Journal of Immunology

Targeted Gene Disruption Demonstrates That P-Selectin Glycoprotein Ligand 1 (Psgl-1) Is Required for P-Selectin–Mediated but Not E-Selectin–Mediated Neutrophil Rolling and Migration

Jing Yang, Takako Hirata, Kevin Croce, +6

The Journal of Experimental Medicine

Cell AdhesionE-selectin–mediated Neutrophil RollingImmunologyImmune RegulationPathology +18

Two thromboxane A2 receptor isoforms in human platelets. Opposite coupling to adenylyl cyclase with different sensitivity to Arg60 to Leu mutation.

Takako Hirata, Fumitaka Ushikubi, Akira Kakizuka, +2

Journal of Clinical Investigation

ImmunologyPathologyThromboxane A2Molecular PharmacologyThrombosis +16

Arg60 to Leu mutation of the human thromboxane A2 receptor in a dominantly inherited bleeding disorder.

Takako Hirata, Akira Kakizuka, Fumitaka Ushikubi, +3

Journal of Clinical Investigation

ThrombopoiesisThrombosisSignal TransductionInherited Human DisordersBlood Platelet +13

P-Selectin Glycoprotein Ligand 1 (Psgl-1) Is a Physiological Ligand for E-Selectin in Mediating T Helper 1 Lymphocyte Migration

Takako Hirata, Glenn Merrill‐Skoloff, Melissa Aab, +3

The Journal of Experimental Medicine

T-regulatory CellImmunologyImmune RegulationImmunologic MechanismAntigen Processing +16

Tumor Cells Enhance Their Own CD44 Cleavage and Motility by Generating Hyaluronan Fragments

Kazuki N. Sugahara, Takako Hirata, Haruko Hayasaka, +3

Journal of Biological Chemistry

Own Cd44 CleavageMia Paca-2Cell AdhesionGlycobiologyImmunology +17

Prostaglandin E₂–prostoglandin E receptor subtype 4 (EP4) signaling mediates UV irradiation-induced systemic immunosuppression

Kitipong Soontrapa, Tetsuya Honda, Daiji Sakata, +8

Proceedings of the National Academy of Sciences

InflammationSignal TransductionMolecular PhysiologySignaling PathwayUv Irradiation +13

Prostaglandin E2 promotes Th1 differentiation via synergistic amplification of IL-12 signalling by cAMP and PI3-kinase

Chengcan Yao, Takako Hirata, Kitipong Soontrapa, +3

Nature Communications

CD43 Functions as a Ligand for E-Selectin on Activated T Cells

Masanori Matsumoto, Kazuyuki Atarashi, Eiji Umemoto, +4

The Journal of Immunology

Rolling of Th1 Cells via P-Selectin Glycoprotein Ligand-1 Stimulates LFA-1-Mediated Cell Binding to ICAM-1

Kazuyuki Atarashi, Takako Hirata, Masanori Matsumoto, +2

The Journal of Immunology