Matthew Wortham

Expression of Constitutive Androstane Receptor, Hepatic Nuclear Factor 4α, and P450 Oxidoreductase Genes Determines Interindividual Variability in Basal Expression and Activity of a Broad Scope of Xenobiotic Metabolism Genes in the Human Liver

Matthew Wortham, Maciej Czerwiński, Lin He et al. · Drug Metabolism and Disposition · 2007 · 145 citations

Medicine, Biochemistry, Pharmacology +17

Extensive Evolutionary Changes in Regulatory Element Activity during Human Origins Are Associated with Altered Gene Expression and Positive Selection

Yoichiro Shibata, Nathan C. Sheffield, Olivier Fédrigo et al. · PLoS Genetics · 2012 · 143 citations · Full text

Life Sciences, Evolutionary Biology, Genetics +15

OTX2 Is Critical for the Maintenance and Progression of Shh-Independent Medulloblastomas

David Cory Adamson, Qun Shi, Matthew Wortham et al. · Cancer Research · 2009 · 125 citations · Full text

Medicine, Genetics, Oncology +17

Global identification of MLL2-targeted loci reveals MLL2’s role in diverse signaling pathways

Changcun Guo, Chun-Chi Chang, Matthew Wortham et al. · Proceedings of the National Academy of Sciences · 2012 · 103 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

The Transition from Fatty Liver to NASH Associates with SAMe Depletion in db/db Mice Fed a Methionine Choline-Deficient Diet

Matthew Wortham, Lin He, Maxwell A. Gyamfi et al. · Digestive Diseases and Sciences · 2008 · 84 citations

Life Sciences, Biochemistry, Nutritional Sciences +17