Geranylgeranylated Rho Small GTPase(s) Are Essential for the Degradation of p27 and Facilitate the Progression from G1 to S Phase in Growth-stimulated Rat FRTL-5 Cells

Aizan Hirai, Susumu Nakamura, Yoshihiko Noguchi, +9

Journal of Biological Chemistry

Azithromycin, a 15-membered macrolide antibiotic, inhibits influenza A(H1N1)pdm09 virus infection by interfering with virus internalization process

Dat Huu Tran, Ryuichi Sugamata, Tomoyasu Hirose, +12

The Journal of Antibiotics

15-Membered MacrolideVirus InfectionImmunologyAntiviral TherapyVirology +8

Geranylgeranyl-Pyrophosphate, an Isoprenoid of Mevalonate Cascade, Is a Critical Compound for Rat Primary Cultured Cortical Neurons to Protect the Cell Death Induced by 3-Hydroxy-3-Methylglutaryl-CoA Reductase Inhibition

Tomoaki Tanaka, Ichiro Tatsuno, Daigaku Uchida, +8

Journal of Neuroscience

ApoptosisCell Death InducedCell DeathGlucocorticoidCellular Physiology +16

Clinical Characteristics of Myeloperoxidase Antineutrophil Cytoplasmic Antibody-Associated Vasculitis Caused by Antithyroid Drugs

Jaeduk Yoshimura Noh, S. Yasuda, Shotaro Sato, +11

The Journal of Clinical Endocrinology & Metabolism

Development of highly selective casein kinase 1δ/1ε (CK1δ/ε) inhibitors with potent antiproliferative properties

Mathieu Bibian, Ronald J. Rahaim, Jun Yong Choi, +12

Bioorganic & Medicinal Chemistry Letters

Systems PharmacologyMolecular PharmacologySelective CaseinPotent Antiproliferative PropertiesMedicine +8

Hrr25/CK1δ-directed release of Ltv1 from pre-40S ribosomes is necessary for ribosome assembly and cell growth

Homa Ghalei, Franz X. Schaub, Joanne R. Doherty, +5

The Journal of Cell Biology

Protein Quality ControlTranscriptional RegulationYeast Homologue Hrr25Cell RegulationMolecular Regulation +13

Therapeutic targeting of casein kinase 1δ in breast cancer

Laura H. Rosenberg, M. Lafitte, Víctor Quereda, +10

Science Translational Medicine

Regulation of FRTL-5 Thyroid Cell Growth by Phosphatidylinositol (OH) 3 Kinase-Dependent Akt-Mediated Signaling

Jun Saito, Aimee D. Kohn, Richard A. Roth, +7

Thyroid

Newly Synthesized Rho A, Not Ras, Is Isoprenylated and Translocated to Membranes Coincident with Progression of the G1 to S Phase of Growth-stimulated Rat FRTL-5 Cells

Yoshihiko Noguchi, Susumu Nakamura, Tatsuji Yasuda, +4

Journal of Biological Chemistry

The Flavonoid Quercetin Regulates Growth and Gene Expression in Rat FRTL-5 Thyroid Cells

Cesidio Giuliani, Yoshihiko Noguchi, Norikazu Harii, +6

Endocrinology

Protein Kinase ABiochemistryThyroid FunctionMedicineNatural Sciences +11