Tomoyasu Hirose

Azithromycin, a 15-membered macrolide antibiotic, inhibits influenza A(H1N1)pdm09 virus infection by interfering with virus internalization process

Dat Huu Tran, Ryuichi Sugamata, Tomoyasu Hirose et al. · The Journal of Antibiotics · 2019 · 159 citations

Life Sciences, Infectious Diseases, Microbiology +16

Total Synthesis of (+)-Madindoline A and (−)-Madindoline B, Potent, Selective Inhibitors of Interleukin 6. Determination of the Relative and Absolute Configurations

Toshiaki Sunazuka, Tomoyasu Hirose, Tatsuya Shirahata et al. · Journal of the American Chemical Society · 2000 · 140 citations

Pharmacy, Chemistry, Medicinal Chemistry +11

Spoxazomicins A–C, novel antitrypanosomal alkaloids produced by an endophytic actinomycete, Streptosporangium oxazolinicum K07-0460T

Yuki Inahashi, Masato Iwatsuki, Aki Ishiyama et al. · The Journal of Antibiotics · 2011 · 100 citations

Pharmacy, Botany, Pharmacology +10

Suppression of bone resorption by madindoline A, a novel nonpeptide antagonist to gp130

Masahiko Hayashi, Mun‐Chual Rho, Akiko Enomoto et al. · Proceedings of the National Academy of Sciences · 2002 · 89 citations

Medicine, Medicinal Chemistry, Pharmacology +13

Relative and Absolute Stereochemistries and Total Synthesis of (+)-Macrosphelides A and B, Potent, Orally Bioavailable Inhibitors of Cell−Cell Adhesion

Toshiaki Sunazuka, Tomoyasu Hirose, Yoshihiro Harigaya et al. · Journal of the American Chemical Society · 1997 · 82 citations

Life Sciences, Chemistry, Pharmacology +12