Gram-positive cell walls stimulate synthesis of tumor necrosis factor alpha and interleukin-6 by human monocytes

Didier Heumann, C Barras, A Severin, +2

Infection and Immunity

Immune RegulationImmunologyPathologyCell DeathImmunologic Mechanism +20

Cytokine production after intravenous or peritoneal gram-negative bacterial challenge in mice. Comparative protective efficacy of antibodies to tumor necrosis factor-alpha and to lipopolysaccharide

Gláucia Zanetti, Didier Heumann, J. Gérain, +6

The Journal of Immunology

Control of lipopolysaccharide (LPS) binding and LPS-induced tumor necrosis factor secretion in human peripheral blood monocytes

Didier Heumann, Philippe Gallay, C Barras, +5

The Journal of Immunology

Lipopolysaccharide-binding protein as a major plasma protein responsible for endotoxemic shock.

Philippe Gallay, Didier Heumann, Didier Le Roy, +2

Proceedings of the National Academy of Sciences

ImmunotoxicologyMicrobial PathogensImmunologyCell DeathInnate Immunity +21

Short time exposure to lipopolysaccharide is sufficient to activate human monocytes

Philippe Gallay, C. Victor Jongeneel, C Barras, +4

The Journal of Immunology

IFN-gamma involvement in the severity of gram-negative infections in mice.

J Kohler, Didier Heumann, Gianni Garotta, +4

The Journal of Immunology

Bolus InjectionsMicrobial PathogensInnate Immune SystemImmunologyInnate Immunity +17

Preferential clonogenic deficit of CD8-positive T-lymphocytes infiltrating human solid tumors.

Sylvia Miescher, Michael Stoeck, Lifeng Qiao, +3

PubMed

Lymphoid NeoplasiaHuman Solid TumorsCancer ImmunosurveillanceCd4+ Til ClonesCd8+ Til Subsets +12

Proliferative and cytolytic potentials of purified human tumor‐infiltrating t lymphocytes. Impaired response to mitogen‐driven stimulation despite T‐cell receptor expression

Sylvia Miescher, Michael Stoeck, Lifeng Qiao, +3

International Journal of Cancer

Mode of action of anti-lipopolysaccharide-binding protein antibodies for prevention of endotoxemic shock in mice.

Philippe Gallay, Didier Heumann, Didier Le Roy, +2

Proceedings of the National Academy of Sciences

ImmunologyImmune RegulationLbp PathwayImmunologic MechanismAntigen Processing +18

Lipopolysaccharide (LPS)-Binding Protein In Human Serum Determines The Tumor Necrosis Factor Response Of Monocytes To LPS

Philippe Gallay, C Barras, Peter S. Tobias, +3

The Journal of Infectious Diseases

Tnf ReleaseImmunologyImmune RegulationPathologyCell Death +15