Disposition of the new antidiabetic agent pioglitazone in rats, dogs, and monkeys.

Yoshihiro Maeshiba, Yoshihiro Kiyota, Kenji Yamashita, +3

PubMed

Pharmacological StudyPharmacologyRadioactivity DosePharmacological AgentNeuropharmacology +9

Disposition of idebenone (CV-2619), a new cerebral metabolism improving agent, in rats and dogs.

Hiroshi Torii, Kiyoshi Yoshida, Takuo Kobayashi, +2

Journal of Pharmacobio-Dynamics

Dogs ExcretionNew Cerebral Metabolism14C-labeled IdebenoneOxidative StressCerebral Vascular Regulation +19

Characterization of Conjugated Metabolites of a New Angiotensin II Receptor Antagonist, Candesartan Cilexetil, in Rats by Liquid Chromatography/Electrospray Tandem Mass Spectrometry Following Chemical Derivatization

Takahiro Kondo, Kiyoshi Yoshida, Yoshinobu Yoshimura, +2

Journal of Mass Spectrometry

PharmacotherapyExperimental PharmacologyMedicinal ChemistryElectrospray Mass SpectrometryPharmacological Study +14

Biotransformation of Molsidomine (<i>N</i>-Ethoxycarbonyl-3-morpholinosydnonimine), a New Anti-anginal Agent, in Rats

Shigeharu Tanayama, Yoichi Nakai, Takeshi Fujita, +3

Xenobiotica

Blood Molsidomine LevelPharmacotherapyExperimental PharmacologyPharmaceutical ChemistryNew Anti-anginal Agent +16

Brain distribution of idebenone and its effect on local cerebral glucose utilization in rats

Yasuo Nagai, Kiyoshi Yoshida, Shigehiko Narumi, +2

Archives of Gerontology and Geriatrics

NeurophysiologyNeuroanatomyMedicineNeuroprotectionNeurology +7

METABOLIC FATE OF 5-ETHOXYCARBONYL-3-MORPHOLINOSYDNONIMINE (SIN-10)

Shigeharu Tanayama, Takeshi Fujita, Yoshihiro Shirakawa, +1

The Japanese Journal of Pharmacology

Metabolic FateMedicinal ChemistryPharmacological StudyBiochemistryMedicine +12

Metabolism of 8-Chloro-6-phenyl-4<i>H</i>-s-triazolo[4,3-α][1,4]-benzodiazepine (D–40TA), a New Central Depressant. I. Absorption, Distribution and Excretion in Rats

Shigeharu Tanayama, Yoshihiro Shirakawa, Yoshio Kanai, +1

Xenobiotica

PsychopharmacologyPharmacotherapyExperimental PharmacologyMolecular PharmacologyPharmacological Study +17

Metabolic fate of cephacetrile after parenteral administration in rats and rabbits.

Yoichi Nakai, Yoshio Kanai, Takeshi Fugono, +1

The Journal of Antibiotics

Disposition of the new angiotensin II receptor antagonist candesartan cilexetil in rats and dogs.

Takahiro Kondo, Ken Yoshida, Y. Yoshimura, +2

PubMed

Blood VesselsMolecular PharmacologyApparent Half-lifePharmacological StudyCandesartan Cilexetil +9

Studies on the metabolism of the new antidiabetic agent pioglitazone. Identification of metabolites in rats and dogs.

Yoshihiro Kiyota, Tomoyuki Kondo, Yoshihiro Maeshiba, +5

PubMed

Pharmaceutical SciencePharmacological StudyBiochemistryMedicinePhysiology +13