Hélène Cannelle

Discovery of a Novel and Selective Indoleamine 2,3-Dioxygenase (IDO-1) Inhibitor 3-(5-Fluoro-1<i>H</i>-indol-3-yl)pyrrolidine-2,5-dione (EOS200271/PF-06840003) and Its Characterization as a Potential Clinical Candidate

Stefano Crosignani, Patrick Bingham, Pauline Bottemanne et al. · Journal of Medicinal Chemistry · 2017 · 134 citations · Full text

Identification of a new subset of lymph node stromal cells involved in regulating plasma cell homeostasis

Hsin-Ying Huang, Ana Rivas-Caicedo, François Renevey et al. · Proceedings of the National Academy of Sciences · 2018 · 112 citations · Full text

Fibroblast‐derived IL‐33 is dispensable for lymph node homeostasis but critical for CD8 T‐cell responses to acute and chronic viral infection

Patricia Aparicio‐Domingo, Hélène Cannelle, Matthew B. Buechler et al. · European Journal of Immunology · 2020 · 42 citations · Full text

Abstract 4863: PF-06840003: a highly selective IDO-1 inhibitor that shows good in vivo efficacy in combination with immune checkpoint inhibitors

Joseph R. Tumang, Bruno Gomes, Martin Wythes et al. · Cancer Research · 2016 · 25 citations

Immune Regulation, Immunology, Immunologic Mechanism +20

Nicotinamide Mononucleotide Administration Triggers Macrophages Reprogramming and Alleviates Inflammation During Sepsis Induced by Experimental Peritonitis

Cécile Cros, Marielle Margier, Hélène Cannelle et al. · Frontiers in Molecular Biosciences · 2022 · 25 citations · Full text

Lung Inflammation, Immunology, Immune Regulation +18