Photodamage to human RPE cells by A2-E, a retinoid component of lipofuscin.

F. Schütt, Sallyanne Davies, Jürgen Kopitz, +2

PubMed

Galectin-1 Is a Major Receptor for Ganglioside GM1, a Product of the Growth-controlling Activity of a Cell Surface Ganglioside Sialidase, on Human Neuroblastoma Cells in Culture

Jürgen Kopitz, Carolina Reitzenstein, M. Burchert, +2

Journal of Biological Chemistry

Inhibition of lysosomal degradative functions in RPE cells by a retinoid component of lipofuscin.

Frank G. Holz, F. Schütt, Jürgen Kopitz, +4

PubMed

Negative Regulation of Neuroblastoma Cell Growth by Carbohydrate-dependent Surface Binding of Galectin-1 and Functional Divergence from Galectin-3

Jürgen Kopitz, Carolina Reitzenstein, Sabine André, +5

Journal of Biological Chemistry

Functional DivergenceImmunologyCell ProliferationCytoskeletonCell Growth +17

Proteins Modified by Malondialdehyde, 4-Hydroxynonenal, or Advanced Glycation End Products in Lipofuscin of Human Retinal Pigment Epithelium

F. Schütt, Marion Bergmann, Frank G. Holz, +1

Investigative Ophthalmology & Visual Science

Inhibition of the ATP‐driven proton pump in RPE lysosomes by the major lipofuscin fluorophore A2‐E may contribute to the pathogenesis of age‐related macular degeneration

Marion Bergmann, F. Schütt, Frank G. Holz, +1

The FASEB Journal

Excessive Lipofuscin AccumulationOcular DiseaseMolecular BiologyCytoskeletonAutophagy +17

Nonselective autophagy of cytosolic enzymes by isolated rat hepatocytes.

Jürgen Kopitz, G. O. Kisen, Paul B. Gordon, +2

The Journal of Cell Biology

MitophagyAldo-keto ReductaseCellular PhysiologyOxidative StressSedimentable Organelles +17

Early postoperative delirium after open-heart cardiac surgery is associated with decreased bispectral EEG and increased cortisol and interleukin-6

Konstanze Plaschke, Philipp Fichtenkamm, Christoph Schramm, +5

Intensive Care Medicine

Postoperative DeliriumNeurologic Intensive CareOpen-heart Cardiac SurgeryBrain InjuryDecreased Bispectral Eeg +2

Tumor suppressor p16^INK4a − modulator of glycomic profile and galectin‐1 expression to increase susceptibility to carbohydrate‐dependent induction of anoikis in pancreatic carcinoma cells

Sabine André, Hugo Sanchez‐Ruderisch, Hiroaki Nakagawa, +13

FEBS Journal

Effects of lipid peroxidation products on lipofuscinogenesis and autophagy in human retinal pigment epithelial cells

Tim U. Krohne, Nina Stratmann, Jürgen Kopitz, +1

Experimental Eye Research

Cell AutophagyBiochemistryPhotocarcinogenesisLipid PeroxidationAutophagy +8