Concepedia

Author

Lexian Tong

Zhejiang UniversityORCID

Also Known As

Le-xian Tong, Lexian Tong

12

Publications

140

Citations

8

H-Index

25

Concepts

All Affiliations

Zhejiang UniversityShanghai Institute of Materia MedicaZhejiang LabChinese Academy of SciencesNational Center for Drug Screening
LT

About

Lexian Tong is an author at Zhejiang University specializing in medicine, immunology, and cancer research.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

4

4

66

2

Cell Biology

2

2

31

3

Immunology

2

2

24

4

Natural Sciences

1

1

25

5

Biochemistry

1

1

25

Lexian Tong

×

6

Publications

96

Citations

6

H-Index

YearCitations

Discovery of (R)-5-((5-(1-methyl-1H-pyrazol-4-yl)-4-(methylamino)pyrimidin-2-yl)amino)-3-(piperidin-3-yloxy)picolinonitrile, a novel CHK1 inhibitor for hematologic malignancies

Lexian Tong, Pinrao Song, Kailong Jiang,

European Journal of Medicinal Chemistry

2019

25

Identification of 2-Aminopyrimidine Derivatives as FLT3 Kinase Inhibitors with High Selectivity over c-KIT

Lexian Tong, Peipei Wang, Xuemei Li,

Journal of Medicinal Chemistry

2022

20

Dual inhibition of CHK1/FLT3 enhances cytotoxicity and overcomes adaptive and acquired resistance in FLT3-ITD acute myeloid leukemia

Kailong Jiang, Xuemei Li, Chang Wang,

Leukemia

2022

17

Discovery of new macrophage M2 polarization modulators as multiple sclerosis treatment agents that enable the inflammation microenvironment remodeling

Jinxin Che, Dan Li, Wenxiang Hong,

European Journal of Medicinal Chemistry

2022

14

Downregulation of c-Myc expression confers sensitivity to CHK1 inhibitors in hematologic malignancies

Kailong Jiang, Lexian Tong, Tao Wang,

Acta Pharmacologica Sinica

2021

10

Discovery of 2-Aminopyrimidine Derivatives as Potent Dual FLT3/CHK1 Inhibitors with Significantly Reduced hERG Inhibitory Activities

Xuemei Li, Peipei Wang, Chang Wang,

Journal of Medicinal Chemistry

2023

10

Page 1