The Central Executioner of Apoptosis: Multiple Connections between Protease Activation and Mitochondria in Fas/APO-1/CD95- and Ceramide-induced Apoptosis

Santos A. Susín, Naoufal Zamzami, Maria Castedo, +6

The Journal of Experimental Medicine

Anaphase-Promoting Complex/Cyclosome–Dependent Proteolysis of Human Cyclin a Starts at the Beginning of Mitosis and Is Not Subject to the Spindle Assembly Checkpoint

Stephan Geley, Edgar R. Kramer, Christian Gieffers, +3

The Journal of Cell Biology

Prostate-specific membrane antigen expression in the neovasculature of gastric and colorectal cancers

Michael C. Haffner, Irmgard Kronberger, Jeffrey S. Ross, +10

Human Pathology

UrologyPerineural InvasionColorectal CancersMedicineColorectal Cancer +6

Simultaneous detection of multiple green fluorescent proteins in live cells by fluorescence lifetime imaging microscopy

Rainer Pepperkok, Anthony Squire, Stephan Geley, +1

Current Biology

Fluorescence LifetimeFluorescence MicroscopySimultaneous DetectionLive CellsEngineering +12

The PIDDosome activates p53 in response to supernumerary centrosomes

Luca L. Fava, Fabian Schuler, Valentina C. Sladky, +7

Genes & Development

ChromatinDevelopmental BiologySupernumerary CentrosomesCell DivisionMature Centrosome +11

p14–MP1-MEK1 signaling regulates endosomal traffic and cellular proliferation during tissue homeostasis

David Teis, Nicole Taub, R Kurzbauer, +10

The Journal of Cell Biology

Drug-induced apoptosis is associated with enhanced Fas (Apo-1/CD95) ligand expression but occurs independently of Fas (Apo-1/CD95) signaling in human T-acute lymphatic leukemia cells.

Andreas Villunger, Alexander Egle, Marion Kos, +4

PubMed

Fasl ProteinApoptosisImmunologyCell DeathImmunotherapy +16

Kinetochore motors drive congression of peripheral polar chromosomes by overcoming random arm-ejection forces

Marin Barišić, Paulo Aguiar, Stephan Geley, +1

Nature Cell Biology

ChromatinChromosome DynamicsKinetochore MotorsCell DivisionRandom Arm-ejection Forces +11

Identification of glucocorticoid-response genes in children with acute lymphoblastic leukemia

Stefan Schmidt, Johannes Rainer, Stefan Riml, +12

Blood

The spindle assembly checkpoint is not essential for CSF arrest of mouse oocytes

Chizuko Tsurumi, Steffen Hoffmann, Stephan Geley, +2

The Journal of Cell Biology

OocyteMolecular BiologyCell DeathMeiosis IiCytoskeleton +15