Souty M.Z. Sharkawi

Design, synthesis of novel isoindoline hybrids as COX-2 inhibitors: Anti-inflammatory, analgesic activities and docking study

Madlen B. Labib, Souty M.Z. Sharkawi, Mahmoud El‐Daly · Bioorganic Chemistry · 2018 · 42 citations

Medicinal Chemistry, Novel Isoindoline Hybrids, Anti-inflammatory +10

Novel pyrazole-based COX-2 inhibitors as potential anticancer agents: Design, synthesis, cytotoxic effect against resistant cancer cells, cell cycle arrest, apoptosis induction and dual EGFR/Topo-1 inhibition

Peter A. Halim, Souty M.Z. Sharkawi, Madlen B. Labib · Bioorganic Chemistry · 2022 · 39 citations

Medicinal Chemistry, Medicine, Pharmacology +11

Trans-ferulic acid ameliorates cisplatin-induced testicular damage via suppression of TLR4, P38-MAPK, and ERK1/2 signaling pathways

Emad H. M. Hassanein, Basel A. Abdel‐Wahab, Fares E.M. Ali et al. · Environmental Science and Pollution Research · 2021 · 30 citations

Reductive Stress, Andrology, Urology +7

Empagliflozin and neohesperidin protect against methotrexate-induced renal toxicity via suppression of oxidative stress and inflammation in male rats

Adel T. Osman, Souty M.Z. Sharkawi, Mohamed I.A. Hassan et al. · Food and Chemical Toxicology · 2021 · 28 citations

Inflammation, Urology, Medicine +10

Perindopril ameliorates lipopolysaccharide-induced brain injury through modulation of angiotensin-II/angiotensin-1-7 and related signaling pathways

Ehab A. M. El‐Shoura, Basim Anwar Shehata Messiha, Souty M.Z. Sharkawi et al. · European Journal of Pharmacology · 2018 · 25 citations

Inflammation, Health Sciences, Medicine +14