Yomna I. El‐Gazzar

Synthesis, biological evaluation and molecular modeling study of new (1,2,4-triazole or 1,3,4-thiadiazole)-methylthio-derivatives of quinazolin-4(3 H )-one as DHFR inhibitors

Yomna I. El‐Gazzar, Hanan H. Georgey, Shahenda M. El‐Messery et al. · Bioorganic Chemistry · 2017 · 53 citations

Pharmacy, Medicinal Chemistry, Pharmacology +10

Thiazolo[4,5- d ]pyridazine analogues as a new class of dihydrofolate reductase (DHFR) inhibitors: Synthesis, biological evaluation and molecular modeling study

Menna A. Ewida, Dalal A. Abou El Ella, Deena S. Lasheen et al. · Bioorganic Chemistry · 2017 · 28 citations

Pharmacy, Medicinal Chemistry, Pharmacology +11

Imidazo[2′,1′:2,3]thiazolo[4,5-d]pyridazinone as a new scaffold of DHFR inhibitors: Synthesis, biological evaluation and molecular modeling study

Menna A. Ewida, Dalal A. Abou El Ella, Deena S. Lasheen et al. · Bioorganic Chemistry · 2018 · 26 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14

New quinazolinone‐based derivatives as DHFR/EGFR‐TK inhibitors: Synthesis, molecular modeling simulations, and anticancer activity

Yomna I. El‐Gazzar, Heba R. Ghaiad, Ahmed M. El Kerdawy et al. · Archiv der Pharmazie · 2022 · 18 citations

Medicine, Medicinal Chemistry, Pharmacology +16