Menna A. Ewida

Synthesis, biological evaluation and molecular modeling study of new (1,2,4-triazole or 1,3,4-thiadiazole)-methylthio-derivatives of quinazolin-4(3 H )-one as DHFR inhibitors

Yomna I. El‐Gazzar, Hanan H. Georgey, Shahenda M. El‐Messery et al. · Bioorganic Chemistry · 2017 · 53 citations

Medicinal Chemistry, Molecular Modeling Study, Derivative (Chemistry) +11

Development of pyrolo[2,3-c]pyrazole, pyrolo[2,3-d]pyrimidine and their bioisosteres as novel CDK2 inhibitors with potent in vitro apoptotic anti-proliferative activity: Synthesis, biological evaluation and molecular dynamics investigations

Eman M. Azmy, Mohamed Hagras, Menna A. Ewida et al. · Bioorganic Chemistry · 2023 · 38 citations · Full text

Thiazolo[4,5- d ]pyridazine analogues as a new class of dihydrofolate reductase (DHFR) inhibitors: Synthesis, biological evaluation and molecular modeling study

Menna A. Ewida, Dalal A. Abou El Ella, Deena S. Lasheen et al. · Bioorganic Chemistry · 2017 · 28 citations

Medicinal Chemistry, Molecular Modeling Study, Bioorganic Chemistry +12

Imidazo[2′,1′:2,3]thiazolo[4,5-d]pyridazinone as a new scaffold of DHFR inhibitors: Synthesis, biological evaluation and molecular modeling study

Menna A. Ewida, Dalal A. Abou El Ella, Deena S. Lasheen et al. · Bioorganic Chemistry · 2018 · 26 citations

Molecular Pharmacology, Medicinal Chemistry, Molecular Modeling Study +13

3-Methyl-imidazo[2,1-b]thiazole derivatives as a new class of antifolates: Synthesis, in vitro/in vivo bio-evaluation and molecular modeling simulations

Menna A. Ewida, Heba A. Ewida, Mahmoud S. Ahmed et al. · Bioorganic Chemistry · 2021 · 13 citations

Medicinal Chemistry, Bioorganic Chemistry, Biochemistry +11