Tumor metabolite lactate promotes tumorigenesis by modulating MOESIN lactylation and enhancing TGF-β signaling in regulatory T cells

Jian Gu, Jinren Zhou, Qiuyang Chen, +10

Cell Reports

ImmunologyRegulatory T CellsCancer BiologyTumor BiologyTgf-β Signaling +15

XBP1 deficiency promotes hepatocyte pyroptosis by impairing mitophagy to activate mtDNA-cGAS-STING signaling in macrophages during acute liver injury

Zheng Liu, Mingming Wang, Xun Wang, +6

Redox Biology

MitophagyApoptosisImmunologyMacrophage Sting ActivationCell Death +21

Comparative analysis of the human macrophage inflammatory protein family of cytokines (chemokines) on proliferation of human myeloid progenitor cells. Interacting effects involving suppression, synergistic suppression, and blocking of suppression

Hal E. Broxmeyer, Barbara Sherry, Stephanie Cooper, +5

The Journal of Immunology

FSTL1 promotes liver fibrosis by reprogramming macrophage function through modulating the intracellular function of PKM2

Jianhua Rao, Hao Wang, Ming Ni, +12

Gut

Role of SMAD and Non-SMAD Signals in the Development of Th17 and Regulatory T Cells

Ling Lü, Julie Wang, Feng Zhang, +6

The Journal of Immunology

Lymphocyte DevelopmentT-regulatory CellImmunologyImmune RegulationRegulatory T Cells +18

ATF3-Mediated NRF2/HO-1 Signaling Regulates TLR4 Innate Immune Responses in Mouse Liver Ischemia/Reperfusion Injury

Jianhua Rao, Xiaosheng Qian, G Li, +6

American Journal of Transplantation

InflammationCytokineLiver PhysiologyInnate Immune SystemImmunology +7

Protective effects of total flavonoids of Bidens pilosa L. (TFB) on animal liver injury and liver fibrosis

Liping Yuan, Feihu Chen, Ling Lü, +4

Journal of Ethnopharmacology

InflammationLiver FibrosisMedicineLiver PhysiologyPathology +8

Spermine Alleviates Acute Liver Injury by Inhibiting Liver-Resident Macrophage Pro-Inflammatory Response Through ATG5-Dependent Autophagy

Shun Zhou, Jian Gu, Rui Liu, +7

Frontiers in Immunology

Synergistic effect of TGF‐β superfamily members on the induction of Foxp3⁺ Treg

Ling Lü, Jilin Ma, Xuehao Wang, +9

European Journal of Immunology

Tgf-beta SuperfamilySclerostinLymphocyte DevelopmentT-regulatory CellImmunology +18

Lactoferrin-lipopolysaccharide interactions. Effect on lactoferrin binding to monocyte/macrophage-differentiated HL-60 cells

Keisuke Miyazawa, Charlie Mantel, Ling Lü, +2

The Journal of Immunology