Microglia modulate blood flow, neurovascular coupling, and hypoperfusion via purinergic actions

Eszter Császár, Nikolett Lénárt, Csaba Cserép, +23

The Journal of Experimental Medicine

Dynamic Purinergic ContactsCell DeathSocial SciencesOxidative StressNeuroinflammation +18

<scp>IGF</scp>‐1 deficiency impairs neurovascular coupling in mice: implications for cerebromicrovascular aging

Péter Tóth, Stefano Tarantini, Nicole M. Ashpole, +8

Aging Cell

Pharmacologically-Induced Neurovascular Uncoupling is Associated with Cognitive Impairment in Mice

Stefano Tarantini, Péter Hertelendy, Zsuzsanna Tucsek, +11

Journal of Cerebral Blood Flow & Metabolism

AgingCerebral Vascular RegulationAlzheimer's DiseaseVascular Risk FactorsBrain Aging +14

N,N-Dimethyltryptamine attenuates spreading depolarization and restrains neurodegeneration by sigma-1 receptor activation in the ischemic rat brain

Írisz Szabó, Viktória Varga, Szabolcs Dvorácskó, +13

Neuropharmacology

PharmacotherapyNeurotransmissionSigma-1 Receptor ActivationGlobal Forebrain IschemiaSocial Sciences +20

Spreading depolarization remarkably exacerbates ischemia-induced tissue acidosis in the young and aged rat brain

Ákos Menyhárt, Dániel Zölei-Szénási, Tamás Puskás, +8

Scientific Reports

Unexpected effects of peripherally administered kynurenic acid on cortical spreading depression and related blood&amp;ndash;brain barrier permeability

József Toldi, Olah, Judit Herédi, +14

Drug Design Development and Therapy

Chitosan nanoparticles release nimodipine in response to tissue acidosis to attenuate spreading depolarization evoked during forebrain ischemia

Orsolya M. Tóth, Ákos Menyhárt, Viktória Varga, +8

Neuropharmacology

NanomedicineNeuromodulation (Medicine)NeurophysiologyMedicineAnesthetic Mechanism +9

Large-conductance Ca2+-activated potassium channels are potently involved in the inverse neurovascular response to spreading depolarization

Ákos Menyhárt, Attila E. Farkas, Dániel Péter Varga, +8

Neurobiology of Disease

Hyperpolarization (Biology)NeurophysiologyPhysiologyIon ChannelsSocial Sciences +8

High incidence of adverse cerebral blood flow responses to spreading depolarization in the aged ischemic rat brain

Ákos Menyhárt, Péter Makra, Borbála É. Szepes, +4

Neurobiology of Aging

NeurophysiologyBrain DysfunctionMedicinePhysiologyCerebrospinal Fluid +12

Age or ischemia uncouples the blood flow response, tissue acidosis, and direct current potential signature of spreading depolarization in the rat brain

Ákos Menyhárt, Dániel Zölei-Szénási, Tamás Puskás, +3

American Journal of Physiology-Heart and Circulatory Physiology