Heterozygous<i>HTRA1</i>mutations are associated with autosomal dominant cerebral small vessel disease

Edgard Verdura, Dominique Hervé, Eva Scharrer, +14

Brain

Cerebral small vessel disease-related protease HtrA1 processes latent TGF-β binding protein 1 and facilitates TGF-β signaling

Nathalie Beaufort, Eva Scharrer, Elisabeth Kremmer, +7

Proceedings of the National Academy of Sciences

Proteolytic Regulation of the Urokinase Receptor/CD87 on Monocytic Cells by Neutrophil Elastase and Cathepsin G

Nathalie Beaufort, Dominique Leduc, Jean-Claude Rousselle, +5

The Journal of Immunology

The <i>Pseudomonas aeruginosa</i> LasB Metalloproteinase Regulates the Human Urokinase-Type Plasminogen Activator Receptor through Domain-Specific Endoproteolysis

Dominique Leduc, Nathalie Beaufort, Sophie de Bentzmann, +4

Infection and Immunity

Sequestration of latent TGF-β binding protein 1 into CADASIL-related Notch3-ECD deposits

Jessica Kast, Patrizia Hanecker, Nathalie Beaufort, +5

Acta Neuropathologica Communications

In vitro and in vivo evidence for the role of elastase shedding of CD163 in human atherothrombosis

Juan Antonio Moreno, Almudena Ortega‐Gómez, Sandrine Delbosc, +10

European Heart Journal

Kallikrein-Related Peptidase 4

Valérie Gratio, Nathalie Beaufort, Lina Seiz, +6

American Journal Of Pathology

BiochemistryNatural SciencesPeptoidBiochemical GeneticsChemical Biology +2

Interplay of human tissue kallikrein 4 (hK4) with the plasminogen activation system: hK4 regulates the structure and functions of the urokinase-type plasminogen activator receptor (uPAR)

Nathalie Beaufort, Mekdes Debela, Sabine Creutzburg, +5

Biological Chemistry

ImmunologyPathologyCancer BiologyCellular PhysiologyTumor Biology +15

Interdependence of kallikrein-related peptidases in proteolytic networks

Nathalie Beaufort, Daniel T. Utzschneider, Amelie Schwarz, +6

Biological Chemistry

Common coding variant in <i>SERPINA1</i> increases the risk for large artery stroke

Rainer Malik, Therese Dau, Maria Gonik, +42

Proceedings of the National Academy of Sciences