A novel integrated cytogenetic and genomic classification refines risk stratification in pediatric acute lymphoblastic leukemia

Anthony V. Moorman, Amir Enshaei, Claire Schwab, +10

Blood

EBF1-PDGFRB fusion in pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL): genetic profile and clinical implications

Claire Schwab, Sarra Ryan, Lucy Chilton, +13

Blood

Time, pattern, and outcome of medulloblastoma relapse and their association with tumour biology at diagnosis and therapy: a multicentre cohort study

Rebecca M. Hill, Stacey Richardson, Ed C. Schwalbe, +13

The Lancet Child & Adolescent Health

Medulloblastoma group 3 and 4 tumors comprise a clinically and biologically significant expression continuum reflecting human cerebellar development

Daniel Williamson, Ed C. Schwalbe, Debbie Hicks, +15

Cell Reports

Emergence and maintenance of actionable genetic drivers at medulloblastoma relapse

Stacey Richardson, Rebecca M. Hill, Christopher Kui, +27

Neuro-Oncology

The role of the RAS pathway in iAMP21-ALL

Sarra Ryan, Elizabeth Matheson, Paul Sinclair, +19

Leukemia

Disease-associated KBTBD4 mutations in medulloblastoma elicit neomorphic ubiquitylation activity to promote CoREST degradation

Zhuoyao Chen, Rafael M. Ioris, Stacey Richardson, +8

Cell Death and Differentiation

Dormant SOX9-Positive Cells Facilitate MYC-Driven Recurrence of Medulloblastoma

Anna Borgenvik, Karl O. Holmberg, Sara Bolin, +33

Cancer Research

ARF suppression by MYC but not MYCN confers increased malignancy of aggressive pediatric brain tumors

Oliver J. Mainwaring, Holger Weishaupt, Miao Zhao, +14

Nature Communications

Molecular characterisation defines clinically-actionable heterogeneity within Group 4 medulloblastoma and improves disease risk-stratification

Jack Goddard, Jemma Castle, Emily Southworth, +21

Acta Neuropathologica