Jennifer Volquardsen

Loss of PTEN-assisted G2/M checkpoint impedes homologous recombination repair and enhances radio-curability and PARP inhibitor treatment response in prostate cancer

Wael Mansour, Pierre Tennstedt, Jennifer Volquardsen et al. · Scientific Reports · 2018 · 68 citations · Full text

BCL2-overexpressing prostate cancer cells rely on PARP1-dependent end-joining and are sensitive to combined PARP inhibitor and radiation therapy

Christoph Oing, Pierre Tennstedt, Ronald Simon et al. · Cancer Letters · 2018 · 30 citations

Parp Inhibitor, Radiation Therapy, Parp1-dependent End-joining +7

Functional crosstalk between DNA damage response proteins 53BP1 and BRCA1 regulates double strand break repair choice

Ali Bakr, Sabrina Köcher, Jennifer Volquardsen et al. · Radiotherapy and Oncology · 2015 · 27 citations

Chromatin, Genome Instability, Dna Damage +8

Impaired 53BP1/RIF1 DSB mediated end-protection stimulates CtIP-dependent end resection and switches the repair to PARP1-dependent end joining in G1

Ali Bakr, Sabrina Köcher, Jennifer Volquardsen et al. · Oncotarget · 2016 · 27 citations · Full text

A functional <i>ex vivo</i> assay to detect PARP1‐EJ repair and radiosensitization by PARP‐inhibitor in prostate cancer

Sabrina Köcher, Burkhard Beyer, Tobias Lange et al. · International Journal of Cancer · 2018 · 19 citations · Full text