Ageing-associated changes in the human DNA methylome: genomic locations and effects on gene expression

Saara Marttila, Laura Kananen, Sergei Häyrynen, +6

BMC Genomics

Laminin α5 substrates promote survival, network formation and functional development of human pluripotent stem cell-derived neurons in vitro

Anu Hyysalo, Mervi Ristola, Meeri Mäkinen, +3

Stem Cell Research

Integrated clinical, whole-genome, and transcriptome analysis of multisampled lethal metastatic prostate cancer

G. Steven Bova, Heini Kallio, Matti Annala, +9

Molecular Case Studies

Androgen ReceptorEngineeringPathologyMultiomicsTranscriptomics Technology +16

Hemap: An Interactive Online Resource for Characterizing Molecular Phenotypes across Hematologic Malignancies

Petri Pölönen, Juha Mehtonen, Jake Lin, +14

Cancer Research

Data-driven characterization of molecular phenotypes across heterogeneous sample collections

Juha Mehtonen, Petri Pölönen, Sergei Häyrynen, +7

Nucleic Acids Research

EngineeringMultiomicsBioinformatics DatabaseGene Expression ProfilingMolecular Ecology +16

<scp><i>CYP2C19</i></scp> loss‐of‐function alleles and use of omeprazole or esomeprazole increase the risk of cardiovascular outcomes in patients using clopidogrel

Markus Ramste, Markus Ritvos, Sergei Häyrynen, +3

Clinical and Translational Science

Challenges and opportunities for strain verification by whole-genome sequencing

Jenna Gallegos, Sergei Häyrynen, Neil Adames, +1

Scientific Reports

Bone morphogenetic protein 4 regulates micro<scp>RNA</scp> expression in breast cancer cell lines in diverse fashion

Emma‐Leena Alarmo, Riikka Havunen, Sergei Häyrynen, +4

Genes Chromosomes and Cancer

Whole-exome sequencing identifies germline mutation in <i>TP53</i> and <i>ATRX</i> in a child with genomically aberrant AT/RT and her mother with anaplastic astrocytoma

Kristiina Nordfors, Joonas Haapasalo, Ebrahim Afyounian, +9

Molecular Case Studies