Autosomal-dominant hemochrom-atosis is associated with a mutation in the ferroportin (SLC11A3) gene

Giuliana Montosi, Adriana Donovan, Cinzia Garuti, +6

Journal of Clinical Investigation

Iron MetabolismGeneticsGenetic EpidemiologyAutosomal-dominant Hemochrom-atosisPathology +19

Autosomal-dominant hemochrom-atosis is associated with a mutation in the ferroportin (SLC11A3) gene

Giuliana Montosi, Adriana Donovan, Cinzia Garuti, +6

Journal of Clinical Investigation

Iron MetabolismGeneticsGenetic EpidemiologyAutosomal-dominant Hemochrom-atosisPathology +19

STAT3 Is Required for IL-6-gp130–Dependent Activation of Hepcidin In Vivo

Antonello Pietrangelo, U Dierssen, Linda Valli, +6

Gastroenterology

InflammationCytokineLiver PhysiologyImmunologyImmune Regulation +6

Hereditary Hemochromatosis in Adults without Pathogenic Mutations in the Hemochromatosis Gene

Antonello Pietrangelo, Giuliana Montosi, Cinzia Garuti, +6

New England Journal of Medicine

Iron overload in Africans and African-Americans and a common mutation in the SCL40A1 (ferroportin 1) gene☆

Victor R. Gordeuk, Angela Caleffi, Elena Corradini, +14

Blood Cells Molecules and Diseases

Ferroportin 1Common MutationIron MetabolismGeneticsIron Overload +4

The role of the iron responsive element in the control of ferroportin1/IREG1/MTP1 gene expression

Athina Lymboussaki, Elisa Pignatti, Giuliana Montosi, +3

Journal of Hepatology

Iron Responsive ElementBiochemistryFerroportin1/ireg1/mtp1 Gene ExpressionNatural SciencesMetalloprotein +6

Wild-type HFE protein normalizes transferrin iron accumulation in macrophages from subjects with hereditary hemochromatosis

Giuliana Montosi, Paola Paglia, Cinzia Garuti, +4

Blood

Juvenile hemochromatosis associated with pathogenic mutations of adult hemochromatosis genes

Antonello Pietrangelo, Angela Caleffi, Jean Henrion, +6

Gastroenterology

Juvenile HemochromatosisGenetic DisorderGeneticsPathogenesisPathology +4

Bone Morphogenetic Protein Signaling Is Impaired in an Hfe Knockout Mouse Model of Hemochromatosis

Elena Corradini, Cinzia Garuti, Giuliana Montosi, +5

Gastroenterology

SclerostinDevelopmental BiologyBone Morphogenic ProteinOsteoporosisHeme Homeostasis +4

BMP6 Treatment Compensates for the Molecular Defect and Ameliorates Hemochromatosis in Hfe Knockout Mice

Elena Corradini, Paul J. Schmidt, Delphine Meynard, +7

Gastroenterology

Knockout MouseHfe Knockout MiceMolecular DefectAutoimmune DiseaseImmunology +7