BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism

Billy Andriopoulos, Elena Corradini, Yin Xia, +8

Nature Genetics

Hepcidin ExpressionBiochemistryHeme HomeostasisIron MetabolismLiver Physiology +10

STAT3 Is Required for IL-6-gp130–Dependent Activation of Hepcidin In Vivo

Antonello Pietrangelo, U Dierssen, Linda Valli, +6

Gastroenterology

InflammationCytokineLiver PhysiologyImmunologyImmune Regulation +6

Iron overload in Africans and African-Americans and a common mutation in the SCL40A1 (ferroportin 1) gene☆

Victor R. Gordeuk, Angela Caleffi, Elena Corradini, +14

Blood Cells Molecules and Diseases

Ferroportin 1Common MutationIron MetabolismGeneticsIron Overload +4

Serum and liver iron differently regulate the bone morphogenetic protein 6 (BMP6)-SMAD signaling pathway in mice

Elena Corradini, Delphine Meynard, Qifang Wu, +4

Hepatology

EASL Clinical Practice Guidelines on haemochromatosis

Heinz Zoller, Benedikt Schaefer, Annick Vanclooster, +6

Journal of Hepatology

Laboratory MedicineMedicineLaboratory Hematology

Juvenile hemochromatosis associated with pathogenic mutations of adult hemochromatosis genes

Antonello Pietrangelo, Angela Caleffi, Jean Henrion, +6

Gastroenterology

Juvenile HemochromatosisGenetic DisorderGeneticsPathogenesisPathology +4

Bone Morphogenetic Protein Signaling Is Impaired in an Hfe Knockout Mouse Model of Hemochromatosis

Elena Corradini, Cinzia Garuti, Giuliana Montosi, +5

Gastroenterology

SclerostinDevelopmental BiologyBone Morphogenic ProteinOsteoporosisHeme Homeostasis +4

Regulation of TMPRSS6 by BMP6 and iron in human cells and mice

Delphine Meynard, Valentina Vaja, Chia Chi Sun, +10

Blood

BMP6 Treatment Compensates for the Molecular Defect and Ameliorates Hemochromatosis in Hfe Knockout Mice

Elena Corradini, Paul J. Schmidt, Delphine Meynard, +7

Gastroenterology

Knockout MouseHfe Knockout MiceMolecular DefectAutoimmune DiseaseImmunology +7

Iron Regulation of Hepcidin Despite Attenuated Smad1,5,8 Signaling in Mice Without Transferrin Receptor 2 or Hfe

Elena Corradini, Molly Rozier, Delphine Meynard, +7

Gastroenterology

InflammationMolecular PhysiologySignal TransductionBiochemistryIron Metabolism +12