Concepedia

James H. Nettles

JH

Statistics

Publications

22

Citations

2.4K

H-Index

18

Active since

2001

Affiliations

Emory University(Current)

Novartis (Switzerland)

Johns Hopkins University Center for AIDS Research

Winship Cancer Institute

Novartis (China)

James H. Nettles is an author at Emory University specializing in pharmacology, medicinal chemistry, and drug discovery.

Publications per year

2001–2018

22

Publications

22

The Binding Mode of Epothilone A on α,ß-Tubulin by Electron Crystallography

James H. Nettles, Huilin Li, Ben Cornett et al. · Science · 2004 · 419 citations

, , +17

Polyoxometalate HIV-1 Protease Inhibitors. A New Mode of Protease Inhibition

Deborah A. Judd, James H. Nettles, Neysa Nevins et al. · Journal of the American Chemical Society · 2001 · 368 citations

, , +15

The binding conformation of Taxol in β-tubulin: A model based on electron crystallographic density

James P. Snyder, James H. Nettles, Ben Cornett et al. · Proceedings of the National Academy of Sciences · 2001 · 363 citations · Full text

, , +15

Bridging Chemical and Biological Space:  “Target Fishing” Using 2D and 3D Molecular Descriptors

James H. Nettles, Jeremy L. Jenkins, Andreas Bender et al. · Journal of Medicinal Chemistry · 2006 · 211 citations

, , +17

Paclitaxel-resistant cells have a mutation in the paclitaxel-binding region of β-tubulin (Asp26Glu) and less stable microtubules

Malathi Hari, Frank Loganzo, Tami Annable et al. · Molecular Cancer Therapeutics · 2006 · 147 citations

, , +17

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