Concepedia

James H. Nettles

JH

22

Publications

2.3K

Citations

18

H-Index

2001

Active since

Affiliations

Emory University(Current)

Novartis (Switzerland)

Johns Hopkins University Center for AIDS Research

Winship Cancer Institute

Lawrence Berkeley National Laboratory

James H. Nettles is an author at Emory University specializing in medicine, pharmacology, and drug discovery.

Top concepts

Publications per year

2001–2018

22

Publications

22

The Binding Mode of Epothilone A on α,ß-Tubulin by Electron Crystallography

James H. Nettles, Huilin Li, Ben Cornett et al. · Science · 2004 · 419 citations

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Polyoxometalate HIV-1 Protease Inhibitors. A New Mode of Protease Inhibition

Deborah A. Judd, James H. Nettles, Neysa Nevins et al. · Journal of the American Chemical Society · 2001 · 366 citations

The binding conformation of Taxol in β-tubulin: A model based on electron crystallographic density

James P. Snyder, James H. Nettles, Ben Cornett et al. · Proceedings of the National Academy of Sciences · 2001 · 361 citations · Full text

Bridging Chemical and Biological Space:  “Target Fishing” Using 2D and 3D Molecular Descriptors

James H. Nettles, Jeremy L. Jenkins, Andreas Bender et al. · Journal of Medicinal Chemistry · 2006 · 208 citations

Paclitaxel-resistant cells have a mutation in the paclitaxel-binding region of β-tubulin (Asp26Glu) and less stable microtubules

Malathi Hari, Frank Loganzo, Tami Annable et al. · Molecular Cancer Therapeutics · 2006 · 146 citations

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