Michael O. Hottiger

Genomic Instability and Aging-like Phenotype in the Absence of Mammalian SIRT6

Raúl Mostoslavsky, Katrin F. Chua, David B. Lombard et al. · Cell · 2006 · 1.6K citations · Full text

Lifespan Extension, Chromatin, Genome Instability +10

p53 inhibition by the LANA protein of KSHV protects against cell death

Jacques Friborg, Wing‐Pui Kong, Michael O. Hottiger et al. · Nature · 1999 · 706 citations

Cell Regulation, Apoptosis, Immunology +11

A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation

Gyula Timinszky, Susanne Till, Paul O. Hassa et al. · Nature Structural & Molecular Biology · 2009 · 405 citations

Chromatin, Chromatin Structure, Chromatin Remodeling +7

Proteome-wide Identification of Poly(ADP-Ribosyl)ation Targets in Different Genotoxic Stress Responses

Stephanie Jungmichel, Florian Rosenthal, Matthias Altmeyer et al. · Molecular Cell · 2013 · 376 citations · Full text

Reductive Stress, Medicine, Natural Sciences +9

SIRT2 regulates NF-κB-dependent gene expression through deacetylation of p65 Lys310

Karin Rothgiesser, Süheda Erener, Susanne Waibel et al. · Journal of Cell Science · 2010 · 363 citations · Full text