A LRRK2-Dependent EndophilinA Phosphoswitch Is Critical for Macroautophagy at Presynaptic Terminals

Sandra‐Fausia Soukup, Sabine Kuenen, Roeland Vanhauwaert, +10

Neuron

Signal TransductionPathogenesisAutophagyPresynaptic TerminalsEndocytic Pathway +9

Restricted Location of PSEN2/γ-Secretase Determines Substrate Specificity and Generates an Intracellular Aβ Pool

Ragna Sannerud, Cary Esselens, Paulina Ejsmont, +27

Cell

Intracellular Aβ PoolProtein SecretionProtein FunctionSignal TransductionSynaptic Signaling +8

Mitochondria metabolism sets the species-specific tempo of neuronal development

Ryohei Iwata, Pierre Casimir, Emir Erkol, +24

Science

Brain DevelopmentMitochondria MetabolismNeuronal DevelopmentOxidative StressHuman Brain Development +15

Deficiency of parkin and PINK1 impairs age-dependent mitophagy in Drosophila

Tom Cornelissen, Sven Vilain, Katlijn Vints, +3

eLife

A prion-like protein regulator of seed germination undergoes hydration-dependent phase separation

Yanniv Dorone, Steven Boeynaems, Eduardo Flores, +16

Cell

EngineeringProtein FoldingNatural SciencesMolecular BiologySeed Germination +7

Mechanisms of stretch-mediated skin expansion at single-cell resolution

Mariaceleste Aragona, Alejandro Sifrim, Milan Malfait, +14

Nature

Skin DevelopmentCutaneous BiologyDermatologyMatrix BiologyStretch-mediated Skin Expansion +6

Molecular understanding of label-free second harmonic imaging of microtubules

Valérie Van Steenbergen, Werend Boesmans, Z. Li, +7

Nature Communications

A novel approach to analyze lysosomal dysfunctions through subcellular proteomics and lipidomics: the case of NPC1 deficiency

Arun Kumar Tharkeshwar, Jesse Trekker, Wendy Vermeire, +16

Scientific Reports

Fungal β-1,3-Glucan Increases Ofloxacin Tolerance of Escherichia coli in a Polymicrobial E. coli/Candida albicans Biofilm

Katrijn De Brucker, Yulong Tan, Katlijn Vints, +7

Antimicrobial Agents and Chemotherapy

A Modular Organization of LRR Protein-Mediated Synaptic Adhesion Defines Synapse Identity

Anna Schroeder, Jeroen Vanderlinden, Katlijn Vints, +5

Neuron