Edward J. Duffy

The active site of factor IXa is located far above the membrane surface and its conformation is altered upon association with factor VIIIa. A fluorescence study.

Vasantha P. Mutucumarana, Edward J. Duffy, Pete Lollar et al. · Journal of Biological Chemistry · 1992 · 104 citations · Full text

Proteinlipid Interaction, Immunocytochemical Technique, Biochemistry +14

Binding of factor VIIIa and factor VIII to factor IXa on phospholipid vesicles.

Edward J. Duffy, Ernest T. Parker, Vasantha P. Mutucumarana et al. · Journal of Biological Chemistry · 1992 · 87 citations · Full text

Proteinlipid Interaction, Molecular Biology, Complex Formation +19

Intrinsic pathway activation of factor X and its activation peptide-deficient derivative, factor Xdes-143-191.

Edward J. Duffy, Pete Lollar · Journal of Biological Chemistry · 1992 · 57 citations · Full text

Activation Peptide, Molecular Regulation, Molecular Biology +21

Mechanism-Based Isocoumarin Inhibitors for Blood Coagulation Serine Proteases. Effect of the 7-Substituent in 7-Amino-4-chloro-3-(isothioureidoalkoxy)isocoumarins on Inhibitory and Anticoagulant Potency

Chih-Min Kam, John E. Kerrigan, R. Richard Plaskon et al. · Journal of Medicinal Chemistry · 1994 · 52 citations

Allosteric modulation of the activity of thrombin

Edward J. Duffy, Herbert Angliker, Bernard Le Bonniec et al. · Biochemical Journal · 1997 · 13 citations · Full text

Molecular Biology, Allosteric Modulation, Chemical Biology +17