Bernard Le Bonniec

Evaluation of Prothrombin Complex Concentrate and Recombinant Activated Factor VII to Reverse Rivaroxaban in a Rabbit Model

Anne Godiér, Anastasia Miclot, Bernard Le Bonniec et al. · Anesthesiology · 2011 · 242 citations · Full text

Glu-192----Gln substitution in thrombin mimics the catalytic switch induced by thrombomodulin.

Bernard Le Bonniec, Charles T. Esmon · Proceedings of the National Academy of Sciences · 1991 · 142 citations · Full text

Protein Assembly, Gln Substitution, Catalytic Switch +18

Evaluation of recombinant activated factor VII, prothrombin complex concentrate, and fibrinogen concentrate to reverse apixaban in a rabbit model of bleeding and thrombosis

Anne‐Céline Martin, Bernard Le Bonniec, Anne‐Marie Fischer et al. · International Journal of Cardiology · 2013 · 95 citations

Thrombopoiesis, Thrombosis, Fibrinogen Concentrate +12

Thrombin Glu-39 restricts the P'3 specificity to nonacidic residues

Bernard Le Bonniec, Ross T. A. MacGillivray, Charles T. Esmon · Journal of Biological Chemistry · 1991 · 90 citations · Full text

Residue 39, Thrombosis, Protein Chemistry +14

Covalent structures of beta and gamma autolytic derivatives of human alpha-thrombin.

Jean‐Paul Boissel, Bernard Le Bonniec, Marie‐Josèphe Rabiet et al. · Journal of Biological Chemistry · 1984 · 83 citations · Full text