Alexander Renwick

The spliceosome is a therapeutic vulnerability in MYC-driven cancer

Tiffany Hsu, Lukas M. Simon, Nicholas J. Neill et al. · Nature · 2015 · 524 citations · Full text

Medicine, Molecular Biology, Oncology +14

Integrative genomic analysis of the human immune response to influenza vaccination

Luis M. Franco, Kristine L Bucasas, Janet Wells et al. · eLife · 2013 · 139 citations · Full text

Life Sciences, Genetics, Immunology +16

HER2 Reactivation through Acquisition of the HER2 L755S Mutation as a Mechanism of Acquired Resistance to HER2-targeted Therapy in HER2+ Breast Cancer

Xiaowei Xu, Carmine De Angelis, Kathleen A. Burke et al. · Clinical Cancer Research · 2017 · 129 citations · Full text

Medicine, Genetics, Oncology +15

Mutations in the transcriptional repressor REST predispose to Wilms tumor

Shazia Mahamdallie, Sandra Hanks, Kristen L. Karlin et al. · Nature Genetics · 2015 · 83 citations

Life Sciences, Genetics, Molecular Biology +14

Combinatorial inhibition of PTPN12-regulated receptors leads to a broadly effective therapeutic strategy in triple-negative breast cancer

Amritha Nair, Hsiang-Ching Chung, Tingting Sun et al. · Nature Medicine · 2018 · 83 citations

Medicine, Oncology, Pharmacology +12