Dan Norris

Suppressing transthyretin production in mice, monkeys and humans using 2nd-Generation antisense oligonucleotides

Elizabeth J. Ackermann, Shuling Guo, Merrill D. Benson et al. · Amyloid · 2016 · 138 citations

Life Sciences, Molecular Biology, Pharmacology +16

Characterization of Target mRNA Reduction Through <i>In Situ</i> RNA Hybridization in Multiple Organ Systems Following Systemic Antisense Treatment in Animals

Gene Hung, Xiaokun Xiao, Raechel Peralta et al. · Nucleic Acid Therapeutics · 2013 · 126 citations

Life Sciences, Medicinal Chemistry, Molecular Biology +16

Antisense oligonucleotide jacifusen for FUS-ALS: an investigator-initiated, multicentre, open-label case series

Neil A. Shneider, Matthew B. Harms, Olivia M. Rifai et al. · The Lancet · 2025 · 28 citations · Full text

Medicine, Molecular Biology, Molecular Medicine +3

Immunogenicity Assessment of Inotersen, a 2′- <i>O</i> -(2-Methoxyethyl) Antisense Oligonucleotide in Animals and Humans: Effect on Pharmacokinetics, Pharmacodynamics, and Safety

Rosie Z. Yu, Yanfeng Wang, Dan Norris et al. · Nucleic Acid Therapeutics · 2020 · 24 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

Antisense oligonucleotide inhibition of cholesteryl ester transfer protein enhances RCT in hyperlipidemic, CETP transgenic, LDLr-/- mice

Thomas A. Bell, Mark J. Graham, Richard Lee et al. · Journal of Lipid Research · 2013 · 20 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17