Lagging-strand replication shapes the mutational landscape of the genome

Martin A.M. Reijns, Harriet Kemp, James Ding, +3

Nature

Genome InstabilityGeneticsGenomic MechanismDna ReplicationGene Evolution +2

Mutations in PLK4, encoding a master regulator of centriole biogenesis, cause microcephaly, growth failure and retinopathy

Carol-Anne Martin, Ilyas Ahmad, Anna Klingseisen, +35

Nature Genetics

Centriole BiogenesisOcular DiseaseDevelopmental BiologyCell RegulationOphthalmology +6

Genome-wide mapping of embedded ribonucleotides and other noncanonical nucleotides using emRiboSeq and EndoSeq

James Ding, Martin S. Taylor, Andrew P. Jackson, +1

Nature Protocols

Dna SequencingOther Noncanonical NucleotidesNatural SciencesGeneticsSequence Analysis +9

Chromatin Looping Links Target Genes with Genetic Risk Loci for Dermatological Traits

Chenfu Shi, Helen Ray-Jones, James Ding, +12

Journal of Investigative Dermatology

Chromatin LoopingEpigenetic ChangeGeneticsImmunologyLinkage Analysis +23

A Model for Improving Health Care Quality for Transgender and Gender Nonconforming Patients

James Ding, Jesse M. Ehrenfeld, E. Kale Edmiston, +2

The Joint Commission Journal on Quality and Patient Safety

NursingFamily MedicineSexual HealthTransgender MedicineGender Identity +10

Thyroglossal duct cyst surgery: A ten-year single institution experience

Justin Ross, Alexander Manteghi, Kimberly Rethy, +2

International Journal of Pediatric Otorhinolaryngology

OtolaryngologyEndocrine SurgerySurgeryGeneral SurgeryMedicine

Characterisation of CD4+ T-cell subtypes using single cell RNA sequencing and the impact of cell number and sequencing depth

James Ding, Samantha Smith, Gisela Orozco, +2

Scientific Reports

Automated Machine Learning Segmentation and Measurement of Urinary Stones on CT Scan

Rilwan Babajide, Katerina Lembrikova, Justin B. Ziemba, +5

Urology

UrologyImage AnalysisMachine Learning SegmentationMedical ImagingEngineering +10

Association of Inherited Mutations in DNA Repair Genes with Localized Prostate Cancer

Daniel J. Lee, Ryan Hausler, Anh N. Le, +8

European Urology

Mapping DNA interaction landscapes in psoriasis susceptibility loci highlights KLF4 as a target gene in 9q31

Helen Ray-Jones, Kate Duffus, Amanda McGovern, +14

BMC Biology